ArticleJournal of optometry
Changes in the thickness of the crystalline lens components before and after cycloplegia in children with different refractive errors.
Article in Journal of optometry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Molecular and Biomechanical Changes in the Anterior Segment of High Myopic Eyes.Annals of biomedical engineering · 2026Review
- Correlation between ocular biological parameters and cycloplegic refractive shift in pediatric myopia.International journal of ophthalmology · 2026Article
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Authors and funding
11 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate changes in the thickness of the crystalline lens components in children with different refractive errors before and after cycloplegia. METHODS AND ANALYSIS: This prospective study recruited 132 right eyes from 132 children (age 5-15 years) with different spherical equivalent (SE) ranging from -6.00 diopters (D) to +6.75 D. We categorized these eyes into non-myopia (N = 30), low-myopia (N = 77), and moderate-myopia (N = 25) groups. The thickness parameters of the crystalline lens components, including lens thickness (LT), lens nucleus thickness (LNT), anterior cortex thickness (ACT), and posterior cortex thickness (PCT), were assessed using optical coherence tomography before and after 0.5 % tropicamide-induced cycloplegia.
resultsAfter cycloplegia, LT significantly decreased from 3.47 ± 0.20 to 3.41 ± 0.20 mm in non-myopia eyes (P < 0.05), and from 3.30 ± 0.17 to 3.27 ± 0.16 mm in low-myopia eyes (P < 0.05), with no significant changes in moderate-myopia eyes (P < 0.05). LNT decreased from 3.15 ± 0.19 to 3.09 ± 0.19 mm in non-myopia eyes (P < 0.05), and from 3.02 ± 0.20 to 2.99 ± 0.17 mm in low-myopia eyes (P < 0.01), with no reduction observed in moderate-myopia eyes (P > 0.05). Cycloplegia-induced changes in ACT and PCT (all P > 0.05) did not differ significantly between the groups. SE was positively correlated with LT and LNT before (Pearson's r = 0.353 and 0.272, respectively; both P < 0.05) and after cycloplegia (r = 0.285 and 0.198, respectively; both P < 0.05).
conclusionsLT and LNT significantly decreased after cycloplegia induced by 0.5 % tropicamide in children with non-myopia and low-myopia, while neither ACT nor PCT changed significantly. SE was positively correlated with LT and LNT.
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