Evidence map›Paper›PMID 40036779›Full record

ArticleSleep2025

Artificial intelligence or sleep experts: comparing polysomnographic sleep staging in children and adolescents.

Annemette L Moeller, Mathias Perslev, Cecilie Paulsrud, Steffen U Thorsen, Helle Leonthin, Nanette M Debes, Jannet Svensson, Poul Jennum

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Annemette L MoellerDepartment of Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.
Mathias PerslevDepartment of Clinical Neurophysiology, Danish Center for Sleep Medicine, Glostrup, Denmark.
Cecilie PaulsrudDepartment of Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.ORCID 0000-0002-2255-3322
Steffen U ThorsenDepartment of Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.
Helle LeonthinDepartment of Clinical Neurophysiology, Danish Center for Sleep Medicine, Glostrup, Denmark.
Nanette M DebesDepartment of Pediatrics, Herlev and Gentofte University Hospital, Herlev, Denmark.
Jannet SvenssonDepartment of Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.
Poul JennumDepartment of Clinical Neurophysiology, Danish Center for Sleep Medicine, Glostrup, Denmark.ORCID 0000-0001-6986-5254

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesThe manual annotation of polysomnography (PSG) hypnograms is difficult and time-consuming. U-Sleep is an alternative, fast, and publicly available, automated sleep staging system evaluated in adult PSGs. In this study, we compare the staging done by sleep experts and U-sleep in a pediatric sample.

methodsPSGs from 56 children aged 6-17 years old (healthy or with a chronic disease) were compared manually annotated with the result of U-sleep. The two outcomes were compared using F1 overlap scores, accuracy, Cohen's kappa, and correlation coefficients. A qualitative analysis of the most significant systematic differences between the manual and automated scoring was performed.

resultsU-sleep matched the manually scored hypnograms with an overall mean F1 score (predicted performance) of 0.75 and reached an accuracy of 83.9% and an overall kappa value of 0.77. The stage-wise F1 scores, U-sleep achieved an F1 score of 0.79 in stage wake, 0.40 in N1, 0.86 in N2, 0.84 in N3, and 0.86 in REM. The correlation between U-sleep and the manual scorer was moderately or very strong in all sleep stages (r = .57-.81).

conclusionsOverall, there is a high degree of agreement between manual and automatic scoring. This suggests that U-sleep is a valid and effective method for identifying sleep stages based on normal PSGs in a pediatric population. The disagreement was within what is expected for interscorer variation. Further evaluation needs of AI sleep-scoring models include analysis of outliers and pathological sleep staging-which is also a challenge in manual annotation.

Indexed as

Artificial IntelligencePolysomnographySleep StagesAdolescentChildFemaleHumansMaleadolescentsartificial intelligencechildrenpediatricpolysomnographysleep stagingU-sleep

Identifiers

PMID40036779

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.