Evidence map›Paper›PMID 40036766›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2025

Impact of aortic root rotation angle on new-onset first-degree atrioventricular block following mitral valve surgery.

Kazuma Handa, Masashi Kawamura, Daisuke Yoshioka, Shunsuke Saito, Takuji Kawamura, Ai Kawamura, Yusuke Misumi, Sho Komukai, Tetsuhisa Kitamura, Shigeru Miyagawa

Abstract read
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kazuma HandaDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0000-0002-6080-2166
Masashi KawamuraDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0000-0002-0695-3203
Daisuke YoshiokaDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0009-0004-4656-7317
Shunsuke SaitoDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Takuji KawamuraDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Ai KawamuraDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Yusuke MisumiDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Sho KomukaiDivision of Biomedical Statistics, Department of Integrated Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0000-0002-4329-2520
Tetsuhisa KitamuraDepartment of Social and Environmental Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0000-0003-0107-0580
Shigeru MiyagawaDepartment of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to classify anatomical variations in aortic root rotation using preoperative three-dimensional transoesophageal echocardiography (3D-TEE), validate these findings with cardiac computed tomography (CT) in patients undergoing mitral valve surgery and evaluate the clinical impact on postoperative atrioventricular conduction disorders.

methodsA total of 126 patients with normal electrocardiograms who underwent isolated mitral valve surgery were included. Anatomical variation was diagnosed using 3D-TEE, and aortic root rotation angle was measured using cardiac CT. New-onset postoperative atrioventricular block (AVB) and bundle branch block were analysed.

resultsVariations of aortic root rotation were classified by 3D-TEE into two categories: 'center rotation' (normal) (85.7%, n = 108/126), where the commissure of the left and non-coronary aortic leaflet was located at center of the anterior mitral leaflet, and 'lateral rotation' (14.3%, n = 18/126), rotated to the lateral trigone side. The aortic root rotation angle, where the interatrial septum was defined as a reference, measured by cardiac CT strongly correlated with 3D-TEE findings ('center rotation' vs 'lateral rotation': 51.6° vs 64.6°, P < 0.001). The incidence of new-onset conduction disorder, all presenting with first-degree AVB, was significantly higher in the 'lateral rotation' than in the 'center rotation' (38.9% [n = 7/18] vs 5.6% [n = 6/108], P < 0.001). Aortic root rotation angles were identified as significant risk factors for postoperative first-degree AVB (odds ratio, 1.05; 95% confidential interval, 1.01-1.09; P = 0.027), with cutoff values of 58.7° predicting persistent new-onset AVB.

conclusionsAortic root rotation angle measured by cardiac CT validated 3D-TEE diagnosis of 'lateral rotation' of the aortic root. 'Lateral rotation' and larger aortic root rotation angles were significant risk factors for postoperative first-degree AVB following mitral valve surgery.

Indexed as

AortaAtrioventricular BlockBundle-Branch BlockCardiac Surgical ProceduresMitral ValveAdultAgedEchocardiography, Three-DimensionalEchocardiography, TransesophagealElectrocardiographyFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective Studiesaortic root rotation positionatrioventricular conduction disordercardiac computed tomographymitral valve surgerythree-dimensional transesophageal echocardiography

Identifiers

PMID40036766
PMCPMC11906399

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.