Evidence map›Paper›PMID 40036669›Full record

ArticleEuropean heart journal. Quality of care & clinical outcomes2025

Quality of care and long-term survival after ST-elevation myocardial infarction in adults with cancer.

Mohamed Dafaalla, Jan Walter Dhillon Shanmuganathan, Muhammad Rashid, Harindra C Wijeysundera, Derek J Roberts, Safi U Khan, Ayman Elbadawi, Islam Y Elgendy, Phillip Freeman, Christian Mallen and 1 more

Abstract readMulticenter Study
In one paragraph

Article in European heart journal. Quality of care & clinical outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Mohamed DafaallaKeele Cardiovascular Research Group, Centre for Prognosis Research, Keele University, Stoke-on-Trent ST5 5BG, UK.ORCID 0000-0003-4625-2775
Jan Walter Dhillon ShanmuganathanDepartment of Cardiology, Aalborg University Hospital, Aalborg 9000, Denmark.
Muhammad RashidKeele Cardiovascular Research Group, Centre for Prognosis Research, Keele University, Stoke-on-Trent ST5 5BG, UK.
Harindra C WijeysunderaInstitute for Clinical Evaluative Sciences, Toronto, Ontario M5T 3M6, Canada.
Derek J RobertsDivision of Vascular and Endovascular Surgery, Department of Surgery and School of Epidemiology and Public Health, Faculty of Medicine University of Ottawa and The Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, Ontario K1N 6N5, Canada.ORCID 0000-0001-6111-6291
Safi U KhanGuthrie Clinic/Robert Packer Hospital, Sayre, PA 18840, USA.
Ayman ElbadawiDepartment of Medicine, Christus Trinity Clinic, Longview, TX 75604, USA.ORCID 0000-0002-4248-781X
Islam Y ElgendyDivision of Cardiovascular Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY 40508, USA.ORCID 0000-0001-9853-7591
Phillip FreemanDepartment of Cardiology, Aalborg University Hospital, Aalborg 9000, Denmark.
Christian MallenSchool of Medicine, Keele University, Keele ST5 5BG, UK.ORCID 0000-0002-2677-1028
Mamas A MamasKeele Cardiovascular Research Group, Centre for Prognosis Research, Keele University, Stoke-on-Trent ST5 5BG, UK.

Funding

Birmingham Biomedical Research CentreDepartment of Health and Social CareNational Institute for Health and Care Research
6 · The paper itself

Abstract

backgroundWhile current evidence suggests that the clinical outcomes of ST-elevation myocardial infarction (STEMI) are worse among patients with cancer, it is unknown what role the quality of care received during admission plays. We aimed to evaluate the association between care quality and patient survival after discharge. METHODS AND

resultsA nationally-linked cohort of STEMI patients (January 2005-March 2019) were obtained from the UK Myocardial Infarction National Audit Project and UK national Hospital Episode Statistics Admitted Patient Care registries. We used the composite opportunity-based quality indicator to measure overall care quality. Survival outcomes were assessed using Cox proportional hazard models and Kaplan-Meier and cumulative survival curves. In total, 6787 STEMI indexed admissions with cancer were identified. Of those, 4340 (63.9%) patients received optimum care, 1320 (19.5%) intermediate care, and 1127(25.2%) low care quality. Patients with low care quality were older [optimum quality median (IQR) = 72.8 (65.1, 79.6), intermediate quality 75.5 (67.9, 82.1), low quality 78.2 (69.2, 84.7)] and more frequently women (optimum quality 21.6%, intermediate quality 27.3%, low quality 35.5%). Compared to patients with optimum care, patients with low care quality had a higher risk of death at 30 days [hazard ratio (HR) 7.0, 95% confidence interval (CI) 5.7-8.7], 1 year (HR 4.0, 95% CI 3.6-4.4), and 5 years (HR 2.6, 95% CI 2.4-2.8). Relative survival analysis revealed that the number of patients who would survive nationally if they received optimal care is 84 (95% CI 67-102), 508 (95% CI 468-548), and 1096 (95% CI 1034-1158) at 30 days, 1 year, and 5 years, respectively. The association between care quality and survival was more profound in the Northwest and Northeast regions.

conclusionQuality of care is closely associated with short- and long-term survival among STEMI patients with cancer. Improving quality of care may save hundreds to thousands of lives in the shorter and longer term.

Indexed as

NeoplasmsQuality of Health CareRegistriesST Elevation Myocardial InfarctionAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesSurvival RateTime FactorsUnited KingdomCancerOutcomesQuality of care

Identifiers

PMID40036669
PMCPMC12587278

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.