Evidence map›Paper›PMID 40036568›Full record

ReviewGenomics, proteomics & bioinformatics2025

Challenges in AI-driven Biomedical Multimodal Data Fusion and Analysis.

Junwei Liu, Xiaoping Cen, Chenxin Yi, Feng-Ao Wang, Junxiang Ding, Jinyu Cheng, Qinhua Wu, Baowen Gai, Yiwen Zhou, Ruikun He and 2 more

Abstract readReview
In one paragraph

Review in Genomics, proteomics & bioinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. [Advances in deep learning multimodal fusion for early diagnosis of knee osteoarthritis].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Junwei LiuGuangzhou National Laboratory, Guangzhou 510005, China.ORCID 0000-0001-8446-4221
Xiaoping CenGuangzhou National Laboratory, Guangzhou 510005, China.ORCID 0000-0002-4848-4302
Chenxin YiGuangzhou National Laboratory, Guangzhou 510005, China.ORCID 0009-0008-6650-9498
Feng-Ao WangGuangzhou National Laboratory, Guangzhou 510005, China.ORCID 0009-0003-1716-4757
Junxiang DingGuangzhou National Laboratory, Guangzhou 510005, China.ORCID 0009-0005-5513-5804
Jinyu ChengGuangzhou National Laboratory, Guangzhou 510005, China.ORCID 0000-0001-8948-1004
Qinhua WuGuangzhou National Laboratory, Guangzhou 510005, China.ORCID 0009-0003-2277-2343
Baowen GaiDepartment of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.ORCID 0009-0005-5934-4267
Yiwen ZhouSchool of Electronics and Communication Engineering, Sun Yat-sen University, Shenzhen 518107, China.ORCID 0009-0007-8243-3051
Ruikun HeBYHEALTH Institute of Nutrition & Health, Guangzhou 510663, China.ORCID 0000-0002-2292-8884
Feng GaoDepartment of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.ORCID 0000-0002-0500-5527
Yixue LiGuangzhou National Laboratory, Guangzhou 510005, China.ORCID 0000-0002-1198-7176

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid development of biological and medical examination methods has vastly expanded personal biomedical information, including molecular, cellular, image, and electronic health record datasets. Integrating this wealth of information enables precise disease diagnosis, biomarker identification, and treatment design in clinical settings. Artificial intelligence (AI) techniques, particularly deep learning models, have been extensively employed in biomedical applications, demonstrating increased precision, efficiency, and generalization. The success of the large language and vision models further significantly extends their biomedical applications. However, challenges remain in learning these multimodal biomedical datasets, such as data privacy, fusion, and model interpretation. In this review, we provide a comprehensive overview of various biomedical data modalities, multimodal representation learning methods, and the applications of AI in biomedical data integrative analysis. Additionally, we discuss the challenges in applying these deep learning methods and how to better integrate them into biomedical scenarios. We then propose future directions for adapting deep learning methods with model pretraining and knowledge integration to advance biomedical research and benefit their clinical applications.

Indexed as

Artificial IntelligenceBiomedical ResearchDeep LearningHumansBiomedical analysisLarge language modelMeta-learningModel interpretationMultimodal learning

Identifiers

PMID40036568
PMCPMC12231560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.