Evidence map›Paper›PMID 40036241›Full record

SynthesisJournal of the Pediatric Infectious Diseases Society2025

Healthcare-Associated Gastroenteritis: Outbreak Report and Systematic Review of the Literature.

Nathan L'Etoile, Morgan A Zalot, Salma Sadaf, Nicole Wittmeyer, Anna Davis, Jordan Mick, Ericka Hayes, Kathleen A Gibbs, Susan E Coffin

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of the Pediatric Infectious Diseases Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nathan L'EtoileDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.ORCID 0009-0006-1489-1686
Morgan A ZalotDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Salma SadafDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Nicole WittmeyerDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Anna DavisDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Jordan MickDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Ericka HayesDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Kathleen A GibbsDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Susan E CoffinDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.

Funding

Infectious Diseases Epidemiology Training GrantT32AI055435 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI LAUTENBACH, EBBING · 2003 to 2023
$6.9M
NIAID NIH HHS T32 AI055435NIH HHS T32AI055435
6 · The paper itself

Abstract

Healthcare-associated gastroenteritis continues to be associated with significant pediatric morbidity and mortality despite the introduction of rotavirus vaccines. Infection prevention (IP) measures are critical in mitigating outbreaks. We describe an outbreak of norovirus and effective IP strategies utilized and calculated the costs associated with the outbreak. To demonstrate the burden of these events, we conducted a systematic review of pediatric healthcare-associated gastroenteritis outbreaks since 1973 to describe changing epidemiologic trends. Twenty-four publications describing 27 outbreaks were included in the final analysis with 293 healthcare-associated cases. Rotavirus (14) and norovirus (7) outbreaks were most commonly described. Limitations include the retrospective nature of included reports, nonuniform data ascertainment and reporting among publications. Norovirus has replaced rotavirus as the most common etiology of healthcare-associated gastroenteritis outbreaks in North America, Europe, and Australia and New Zealand, since the introduction of rotavirus vaccines.

Indexed as

Caliciviridae InfectionsCross InfectionDisease OutbreaksGastroenteritisAustraliaChildHumansNorovirusRotavirusRotavirus InfectionsRotavirus VaccinesRotavirus Vaccinesepidemiologyhealthcare-associated infectionsnorovirusoutbreaksrotavirus

Identifiers

PMID40036241
PMCPMC12022606

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.