Evidence map›Paper›PMID 40036153›Full record

ArticleeLife2025

First evidence for the evolution of host manipulation by tumors during the long-term vertical transmission of tumor cells in

Justine Boutry, Océane Rieu, Lena Guimard, Jordan Meliani, Aurora M Nedelcu, Sophie Tissot, Nikita Stepanskyy, Beata Ujvari, Rodrigo Hamede, Antoine M Dujon and 2 more

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Justine BoutryCREEC/CANECEV (CREES), MIVEGEC, Unité Mixte de Recherches, IRD 224-CNRS 5290 Université de Montpellier, Montpellier, France.ORCID https://orcid.org/0000-0002-0707-1202
Océane RieuCREEC/CANECEV (CREES), MIVEGEC, Unité Mixte de Recherches, IRD 224-CNRS 5290 Université de Montpellier, Montpellier, France.ORCID https://orcid.org/0009-0001-2341-9993
Lena GuimardCREEC/CANECEV (CREES), MIVEGEC, Unité Mixte de Recherches, IRD 224-CNRS 5290 Université de Montpellier, Montpellier, France.
Jordan MelianiCREEC/CANECEV (CREES), MIVEGEC, Unité Mixte de Recherches, IRD 224-CNRS 5290 Université de Montpellier, Montpellier, France.
Aurora M NedelcuDepartment of Biology, University of New Brunswick, Fredericton, Canada.ORCID https://orcid.org/0000-0002-7517-2419
Sophie TissotCREEC/CANECEV (CREES), MIVEGEC, Unité Mixte de Recherches, IRD 224-CNRS 5290 Université de Montpellier, Montpellier, France.
Nikita StepanskyyCREEC/CANECEV (CREES), MIVEGEC, Unité Mixte de Recherches, IRD 224-CNRS 5290 Université de Montpellier, Montpellier, France.
Beata UjvariCREEC/CANECEV (CREES), MIVEGEC, Unité Mixte de Recherches, IRD 224-CNRS 5290 Université de Montpellier, Montpellier, France.ORCID https://orcid.org/0000-0003-2391-2988
Rodrigo HamedeSchool of Biological Sciences, University of Tasmania, Hobart, Australia.
Antoine M DujonCREEC/CANECEV (CREES), MIVEGEC, Unité Mixte de Recherches, IRD 224-CNRS 5290 Université de Montpellier, Montpellier, France.ORCID https://orcid.org/0000-0002-1579-9156
Jácint TökölyiMTA-DE "Momentum" Ecology, Evolution and Developmental Biology Research Group, Department of Evolutionary Zoology, University of Debrecen, Debrecen, Hungary.ORCID https://orcid.org/0000-0002-6908-6493
Fréderic ThomasCREEC/CANECEV (CREES), MIVEGEC, Unité Mixte de Recherches, IRD 224-CNRS 5290 Université de Montpellier, Montpellier, France.ORCID https://orcid.org/0000-0003-2238-1978

Funding

Agence Nationale de la Recherche EVOSEXCAN
6 · The paper itself

Abstract

While host phenotypic manipulation by parasites is a widespread phenomenon, whether tumors, which can be likened to parasite entities, can also manipulate their hosts is not known. Theory predicts that this should nevertheless be the case, especially when tumors (neoplasms) are transmissible. We explored this hypothesis in a cnidarian

Indexed as

Biological EvolutionHydraNeoplasmsAnimalsHost-Parasite Interactionsecologyevolutionary biologyhost–tumor interactionsHydra oligactismanipulationtransmissible tumorsvertical transmission

Identifiers

PMID40036153
PMCPMC11879105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.