Evidence map›Paper›PMID 40036105›Full record

Observational studyThe Indian journal of medical research2025

Methicillin-resistant Staphylococcus aureus (MRSA) carriage among the critical care personnel in a tertiary care hospital in Sikkim: An observational study.

Anusha Subba, Dechen Chomu Tsering

Abstract readObservational Study
In one paragraph

Observational study in The Indian journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anusha SubbaDepartment of Microbiology, Sikkim Manipal Institute of Medical Sciences, Sikkim Manipal University, Gangtok, India.
Dechen Chomu TseringDepartment of Microbiology, Sikkim Manipal Institute of Medical Sciences, Sikkim Manipal University, Gangtok, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background & objectives Persistent nasal colonisation of methicillin-resistant Staphylococcus aureus (MRSA) among healthcare personnel (HCP) remains a significant challenge. MRSA carriers are crucial to the spread of the infection, with healthcare professionals often acting as vectors for both hospital- and community-acquired MRSA. This study aimed to evaluate the MRSA carriage rate among healthcare professionals from critical care units at a tertiary care hospital in Gangtok, Sikkim. Furthermore, the study undertook to analyse antibiotic susceptibility patterns of isolated MSSA and MRSA strains, and identify associated risk factors for MRSA infection. Methods Three hundred samples from healthcare workers (HCW) posted in the critical care units of a tertiary care hospital were cultured and identified by routine biochemical methods. Antibiotic susceptibility test was performed by Kirby Bauer disk diffusion method for all MRSA and MSSA isolates. Association with various risk factors was understood by the Chi square test. Results Nineteen of the 300 participants were identified as nasal MRSA carriers having an overall carriage rate of 6.33 per cent in this study. The prevalence of MRSA was seen to be the highest among the attendants (9.52%), and the highest carriers were from the surgical Intensive Care Unit (ICUs). All the MRSA and MSSA isolates showed 100 per cent resistance to penicillin and 100 per cent susceptibility to linezolid. A significant correlation among hand hygiene practices and patient contact was reported from this study. Interpretation & conclusions Despite existing infection control policies, the MRSA carriage seen in HCWs in critical care units was 6.33 per cent, highlighting the need for regular systematic screening and decolonisation of all healthcare professionals to decrease the carrier status and prevent the spread of infection.

Indexed as

Carrier StateHealth PersonnelMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAdultAnti-Bacterial AgentsCritical CareCross InfectionFemaleHumansIntensive Care UnitsMaleMicrobial Sensitivity TestsMiddle AgedRisk FactorsTertiary Care CentersAnti-Bacterial AgentsCarrierscritical care unitshealthcare workershospital infection controlmethicillin resistant Staphylococcus aureus

Identifiers

PMID40036105
PMCPMC11878663

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.