Evidence map›Paper›PMID 40035965›Full record

ArticleJournal of general internal medicine2025

Diabetes Complications Among Community-Based Health Center Patients with Varying Multimorbidity Patterns.

Ana R Quiñones, Jun Hwang, Nathalie Huguet, Charisse Madlock-Brown, Miguel Marino, Robert Voss, Charles Garven, David A Dorr

Abstract readMulticenter Study
In one paragraph

Article in Journal of general internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ana R QuiñonesDepartment of Family Medicine, Oregon Health & Science University, Portland, OR, USA. quinones@ohsu.edu.ORCID 0000-0001-6554-7734
Jun HwangDepartment of Family Medicine, Oregon Health & Science University, Portland, OR, USA.
Nathalie HuguetDepartment of Family Medicine, Oregon Health & Science University, Portland, OR, USA.
Charisse Madlock-BrownCollege of Nursing, The University of Iowa, Iowa City, IA, USA.
Miguel MarinoDepartment of Family Medicine, Oregon Health & Science University, Portland, OR, USA.
Robert VossResearch Department, OCHIN Inc, Portland, OR, USA.
Charles GarvenNeighborhood Family Practice, Cleveland, OH, USA.
David A DorrDepartment of Medical Informatics & Clinical Epidemiology, Oregon Health & Science University, Portland, OR, USA.

Funding

Aging in Community Health Clinics: Multimorbidity Patterns among Middle-Aged and Older Adults (ACHES)R01AG061386 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI QUINONES, ANA ROMAN · 2019 to 2023
$2.9M
DP20-002 ACE-D: Assess insurance Coverage Expansion on Diabetes complicationsU18DP006536 · DP · OREGON HEALTH & SCIENCE UNIVERSITY · PI HUGUET, NATHALIE · 2020 to 2024
$2.3M
NCCDPHP CDC HHS U18 DP006536NIA NIH HHS R01 AG061386NIA NIH HHS R01AG061386NIDDK NIH HHS U18DP006536
6 · The paper itself

Abstract

backgroundMultimorbidity with diabetes mellitus (DM and ≥ 1 chronic disease) presents challenges to maintaining adequate DM control.

objectiveThis study evaluates the risk of DM-related complications associated with various multimorbidity/DM patterns for patients seen in community-based health centers (CHCs).

designRetrospective cohort study from the ADVANCE multi-state practice-based clinical data network.

participantsStudy included data from 132,765 patients age ≥ 45 years with DM seen in 2493 CHCs across 26 states from 10/01/2015 to 12/31/2019. MAIN MEASURES: We assessed accrual of conditions and risk of experiencing DM complications during follow-up. Primary outcome of DM complication was categorized into acute, microvascular, microvascular (end-stage), macrovascular, or other. Key exposures included mutually exclusive multimorbidity categories: (1) DM + cardiometabolic, (2) DM + other somatic, (3) DM + mental, (4) DM + mental + somatic. KEY

resultsAt baseline, 17.2% of patients had DM only, 55.0% had DM + cardiometabolic multimorbidity, 2.3% had DM + other somatic multimorbidity, 3.0% had DM + mental multimorbidity, and 22.5% had DM + mental + somatic multimorbidity. Most DM-only patients (76.5%) developed multimorbidity with DM by study end. Compared with DM-only, adjusted risk differences of DM complications ranged from 1.4% (acute) to 8.8% (microvascular). DM + mental + somatic multimorbidity was associated with 13.4% (95%CI 12.8-14.1%) higher adjusted risk of experiencing any DM complication.

conclusionsCHCs care for increasingly complex populations of patients with DM. Tailoring disease management strategies to address comorbid cardiovascular and/or mental health conditions may be important to prevent acute, microvascular, and macrovascular complications in these settings.

Indexed as

Community Health CentersDiabetes ComplicationsMultimorbidityAgedCohort StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesUnited StatesCommunity-based health centersDiabetesDiabetes complicationsMultimorbidityMultiple chronic conditionsSafety-net clinics

Identifiers

PMID40035965
PMCPMC12045846

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.