Evidence map›Paper›PMID 40035883›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2025

Predictive ability of frailty scores in surgically managed patients with traumatic spinal injuries: a TQIP analysis.

Maximilian Peter Forssten, Lovisa Ekestubbe, Yang Cao, Ahmad Mohammad Ismail, Ioannis Ioannidis, Babak Sarani, Shahin Mohseni

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Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Maximilian Peter ForsstenDepartment of Orthopedic Surgery, Orebro University Hospital, Orebro, 701 85, Sweden.
Lovisa EkestubbeDepartment of Orthopedic Surgery, Orebro University Hospital, Orebro, 701 85, Sweden.
Yang CaoClinical Epidemiology and Biostatistics, School of Medical Sciences, Faculty of Medicine and Health, Orebro University, Orebro, 701 82, Sweden.
Ahmad Mohammad IsmailDepartment of Orthopedic Surgery, Orebro University Hospital, Orebro, 701 85, Sweden.
Ioannis IoannidisDepartment of Orthopedic Surgery, Orebro University Hospital, Orebro, 701 85, Sweden.
Babak SaraniCenter of Trauma and Critical Care, George Washington University, Washington, DC, USA.
Shahin MohseniSchool of Medical Sciences, Orebro University, Orebro, 702 81, Sweden. mohsenishahin@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFrailty has gained recognition as a crucial determinant of patient outcomes following traumatic spinal injury (TSI), particularly due to its increasing incidence in elderly populations. The aim of the current investigation was therefore to compare the ability of several frailty scores to predict adverse outcomes in surgically managed isolated TSI patients without spinal cord injury.

methodsAll adult patients (18 years or older) who suffered an isolated TSI due to blunt trauma, and required surgical management, were extracted from the 2013-2021 Trauma Quality Improvement Program database. The ability of the Orthopedic Frailty Score (OFS), the Hospital Frailty Risk Score (HFRS), the 11-factor (11-mFI) and 5-factor (5-mFI) modified frailty index, as well as the Johns Hopkins Frailty Indicator to predict adverse outcomes was compared based on the area under the receiver-operating characteristic curve (AUC). Subgroup analyses were also performed on patients who were ≥ 65 years old and those who were injured due to a ground-level fall (GLF).

resultsA total of 39,449 patients were selected from the TQIP database. The 5-mFI and 11-mFI outperformed all other frailty scores when predicting in-hospital mortality (5-mFI AUC: 0.73) (11-mFI AUC: 0.73), any complication (5-mFI AUC: 0.65) (11-mFI AUC: 0.65), and FTR (5-mFI AUC: 0.75) (11-mFI AUC: 0.75). Among the 14,257 geriatric patients, however, the OFS demonstrated the highest predictive ability for in-hospital mortality (AUC: 0.65). The OFS (AUC: 0.64) also performed on the same level as both the 5-mFI (AUC: 0.63) and the 11-mFI (AUC: 0.63) when predicting FTR in this population. Among the 9616 patients who were injured due to a GLF, the OFS performed on par with the 5-mFI and 11-mFI when predicting in-hospital mortality and FTR.

conclusionSimpler scores like the 5-factor modified Frailty Index and Orthopedic Frailty Score outperform or perform on par with more complicated frailty scores when predicting mortality, complications, and failure-to-rescue in surgically managed isolated traumatic spinal injury patients without spinal cord injury, particularly among geriatric patients and those injured in a GLF.

Indexed as

FrailtySpinal InjuriesWounds, NonpenetratingAdultAgedAged, 80 and overDatabases, FactualFemaleHospital MortalityHumansInjury Severity ScoreMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk AssessmentFrailtyHospital frailty risk scoreJohns Hopkins frailty indicatorModified frailty indexMorbidityMortalityOrthopedic frailty scoreTraumatic spinal injury

Identifiers

PMID40035883
PMCPMC11880054

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.