ArticleLangenbeck's archives of surgery2025
Poor bony density can independently trigger higher incidence of adjacent vertebral fracture after percutaneous vertebralplasty: a mono-center retrospective study.
Article in Langenbeck's archives of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Article
- Analysis of risk factors and development of a predictive model for new vertebral fractures subsequent to percutaneous kyphoplasty in patients with single-segment osteoporotic vertebral compression fractures.BMC musculoskeletal disorders · 2026Article
- Changes in PFNA nail position do not influence bone healing and femoral head varus in patients with stable intertrochanteric fractures: a comprehensive clinical and biomechanical study.European journal of medical research · 2026Article
- Modified PHILOS system utilizing a single bone cement calcar screw achieves optimal fixation stability and promotes bone healing: a biomechanical study and corresponding case series.BMC musculoskeletal disorders · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
objectiveSymptomatic adjacent vertebral fractures (AVF) poses a challenge to patient prognosis in osteoporotic vertebral compressive fractures (OVCF) treated by percutaneous vertebralplasty (PVP). This study aimed to identify potential risk factors for AVF, thereby offering theoretical insights for refining patient management strategies and surgical protocols.
methodsClinical data of PVP patients treated between March 2018 and May 2020 were retrospectively analyzed, with an average follow-up period of 30 months. Patients were stratified into two groups based on the presence or absence of recurrent symptomatic AVF. Demographic characteristics and imaging based parameters were assessed to identify potential risk factors for AVF.
resultsDemographic parameters, including age, sex, body mass index, and fracture location (junctional or non-junctional), did not significantly differ between the two groups and were not found to be independent risk factors for AVF. However, patients with AVF exhibited significantly lower bone mineral density, as assessed by T-score and Hounsfield unit (HU) values. Notably, lower HU values emerged as an independent risk factor for AVF. Contrary to expectations, larger vertebral distraction and intervertebral disc cement leakage did not trigger higher incidence of AVF.
conclusionProgression of bony density reduction emerged as the primary driver for the heightened incidence of AVF. Accordingly, anti-osteoporosis therapy should be regarded as an effective strategy for mitigating the risk of AVF in patients undergoing PVP.
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