Evidence map›Paper›PMID 40035756›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

S-nitrosylation-triggered secretion of mycobacterial PknG leads to phosphorylation of SODD to prevent apoptosis of infected macrophages.

Saradindu Saha, Sadhana Roy, Arnab Hazra, Debayan Das, Vimal Kumar, Amit Kumar Singh, Ajay Vir Singh, Rajesh Mondal, Somdeb Bose Dasgupta

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Saradindu Saha *Molecular Immunology and Cellular Microbiology Laboratory, Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Sadhana Roy *Molecular Immunology and Cellular Microbiology Laboratory, Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Arnab HazraMolecular Immunology and Cellular Microbiology Laboratory, Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Debayan DasMolecular Immunology and Cellular Microbiology Laboratory, Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Vimal KumarLaboratory for Animal Experiments, ICMR-National JALMA Institute for Leprosy and Other Mycobacterial Diseases, Agra 282006, India.
Amit Kumar SinghLaboratory for Animal Experiments, ICMR-National JALMA Institute for Leprosy and Other Mycobacterial Diseases, Agra 282006, India.
Ajay Vir SinghDepartment of Microbiology and Molecular Biology, Indian Council of Medical Research (ICMR)-National Japanese Leprosy Mission for Asia (JALMA) Institute for Leprosy and Other Mycobacterial Diseases, Agra 282006, India.
Rajesh MondalDepartment of Bacteriology, National Institute for Research in Tuberculosis, Chennai, Tamil Nadu 600031, India.
Somdeb Bose DasguptaMolecular Immunology and Cellular Microbiology Laboratory, Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.ORCID 0000-0001-5446-9582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tuberculosis-causing agent

Indexed as

ApoptosisBacterial ProteinsCyclic GMP-Dependent Protein KinasesMacrophagesMycobacterium tuberculosisTuberculosisAnimalsMiceMice, Inbred C57BLPhosphorylationTumor Necrosis Factor-alphaBacterial ProteinsCyclic GMP-Dependent Protein KinasesTumor Necrosis Factor-alphaapoptosisphosphorylationprotein kinase GS-nitrosylationSODD

Identifiers

PMID40035756
PMCPMC11912491

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.