Evidence map›Paper›PMID 40035469›Full record

ArticleJournal of cosmetic dermatology2025

Three Calcium Hydroxylapatite-Based Dermal Fillers Marketed in Mexico: Comparison of Particle Size and Shape Using Electron Microscopy.

Gilberto A Sanchez Rico, Silvia Beatriz Andrade Canto

Abstract readComparative Study
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gilberto A Sanchez RicoOneline Beauty Clinic, Cancún, Quintana Roo, Mexico.
Silvia Beatriz Andrade CantoCentro de Investigación Científica de Yucatán, Mérida, Yucatán, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDermal fillers have been a popular choice for cosmetic dermatology procedures, and understanding the physical properties of microparticles used in dermal fillers is crucial for developing safe and effective aesthetic treatments.

aimThis study analyzed three dermal filler products (Radiesse, HarmonyCA, and Hydroxyfill) based on calcium hydroxyapatite microspheres approved for dermal filler procedures in Mexico. MATERIAL AND

methodsThe study used scanning electron microscopic analysis to study the morphology and characteristics of the calcium hydroxyapatite microspheres used in these dermal filler products.

resultsResults revealed important differences in the shape of the microspheres between the three products, which may have implications for their biocompatibility and performance in clinical use.

conclusionsGaining a deeper understanding of these differences enables the improved development of dermal fillers to meet the growing demand for safe and effective aesthetic treatments. This study contributes to building knowledge about the use of microparticles in soft tissue fillers for aesthetic treatments and medical applications.

Indexed as

Cosmetic TechniquesDermal FillersDurapatiteBiocompatible MaterialsHumansMexicoMicroscopy, Electron, ScanningMicrospheresParticle SizeBiocompatible MaterialsDermal FillersDurapatitebiocompatibilityCaHacalcium hydroxyapatitedermal fillerselectron microscopyparticle shapescanning electron microscopysurface structure

Identifiers

PMID40035469
PMCPMC11877991

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Registered trials

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