Evidence map›Paper›PMID 40035430›Full record

ArticleFuture science OA2025

Biodistribution and persistence of human umbilical cord-derived mesenchymal stem cells in NCG mice: a comparative study.

Guangyang Liu, Herui Wang, Xin Li, Yi Mi, Chenliang Zhang, Yaoyao Chen, Li Miao, Haomiao Long, Jun He, Qinggang Ge and 1 more

Abstract read
In one paragraph

Article in Future science OA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Guangyang LiuStem Cell Biology and Regenerative Medicine Apartment, Yi-Chuang Institute of Bio-Industry, Beijing, China.
Herui WangStem Cell Biology and Regenerative Medicine Apartment, Yi-Chuang Institute of Bio-Industry, Beijing, China.ORCID 0000-0003-1221-1254
Xin LiStem Cell Biology and Regenerative Medicine Apartment, Yi-Chuang Institute of Bio-Industry, Beijing, China.
Yi MiStem Cell Biology and Regenerative Medicine Apartment, Yi-Chuang Institute of Bio-Industry, Beijing, China.
Chenliang ZhangStem Cell Biology and Regenerative Medicine Apartment, Yi-Chuang Institute of Bio-Industry, Beijing, China.
Yaoyao ChenStem Cell Biology and Regenerative Medicine Apartment, Yi-Chuang Institute of Bio-Industry, Beijing, China.
Li MiaoStem Cell Biology and Regenerative Medicine Apartment, Yi-Chuang Institute of Bio-Industry, Beijing, China.
Haomiao LongStem Cell Biology and Regenerative Medicine Apartment, Yi-Chuang Institute of Bio-Industry, Beijing, China.
Jun HeCentre for Safety Evaluation and Research of Drugs, Institute of Laboratory Animal Sciences, Chinese Academy of Medical Science, Beijing, China.
Qinggang GeIntensive Care Unit, Peking University Third Hospital, Beijing, China.
Yongjun LiuStem Cell Biology and Regenerative Medicine Apartment, Yi-Chuang Institute of Bio-Industry, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aims to investigate the biodistribution and persistence of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) in NCG mice post-intravenous injection, utilizing

methodshUC-MSCs were labeled with

resultsA biodistribution and persistence pattern was observed in the order of lung > liver > kidney > >spleen, although discrepancies were noted for the liver and kidney.

conclusionEach method exhibited strengths and weaknesses:

Indexed as

89Zr-PET/CTbioluminescenceMesenchymal stromal/stem cellsmultiplex immunohistochemistrypharmacokineticsquantitative polymerase chain reaction

Identifiers

PMID40035430
PMCPMC11881841

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.