Evidence map›Paper›PMID 40035383›Full record

ArticleCancer communications (London, England)2025

Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma.

Katia Mariniello, James F H Pittaway, Barbara Altieri, Kleiton Silva Borges, Irene Hadjidemetriou, Claudio Ribeiro, Gerard Ruiz-Babot, David S Tourigny, Jiang A Lim, Julie Foster and 28 more

Abstract read
In one paragraph

Article in Cancer communications (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. SPP1Journal for immunotherapy of cancer · 2026
    Article
  2. Article
  3. DLK1: a novel therapeutic target in cancer.Endocrine-related cancer · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

38 authors.

Katia MarinielloCentre for Endocrinology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.
James F H PittawayCentre for Endocrinology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0003-0112-8463
Barbara AltieriDivision of Endocrinology and Diabetes, Dept. of Medicine, University Hospital, University of Würzburg, Würzburg, Germany.
Kleiton Silva BorgesDivision of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-0356-922X
Irene HadjidemetriouCentre for Endocrinology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.
Claudio RibeiroDivision of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Gerard Ruiz-BabotDivision of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
David S TourignySchool of Mathematics, University of Birmingham, Birmingham, UK.
Jiang A LimCentre for Endocrinology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.
Julie FosterCentre for Cancer Biomarkers and Biotherapeutics, Barts Cancer Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK.
Julie CleaverCentre for Cancer Biomarkers and Biotherapeutics, Barts Cancer Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK.
Jane SosabowskiCentre for Cancer Biomarkers and Biotherapeutics, Barts Cancer Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK.
Nafis RahmanInstitute of Biomedicine, University of Turku, Turku, Finland.
Milena DoroszkoInstitute of Biomedicine, University of Turku, Turku, Finland.
Constanze HantelDepartment of Endocrinology, Diabetology and Clinical Nutrition, University Hospital Zurich (USZ) and University of Zurich (UZH), Zurich, Switzerland.
Sandra SigalaSection of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Andrea AbateSection of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Mariangela TamburelloSection of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Katja Kiseljak-VassiliadesDivision of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.
Margaret WiermanDivision of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.
Charlotte HallCentre for Endocrinology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.
Laila ParvantaDepartment of Surgery, St Bartholomew's Hospital, West Smithfield, London, UK.
Tarek E Abdel-AzizDepartment of Surgery, University College London Hospitals NHS Foundation Trust, London, UK.
Teng-Teng ChungDepartment of Endocrinology, University College London Hospitals NHS Foundation Trust, London, UK.
Aimee Di MarcoDepartment of Endocrine and Thyroid Surgery, Hammersmith Hospital, Imperial College London, London, UK.
Fausto PalazzoDepartment of Endocrine and Thyroid Surgery, Hammersmith Hospital, Imperial College London, London, UK.
Celso E Gomez-SanchezEndocrine Section, G.V. (Sonny) Montgomery VA Medical Center and the Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, USA.
David R TaylorDepartment of Clinical Biochemistry (Synnovis Analytics), King's College Hospital, London, UK.
Oliver RaynerDepartment of Clinical Biochemistry (Synnovis Analytics), King's College Hospital, London, UK.
Cristina L RonchiInstitute of Metabolism and System Research College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Carles Gaston-MassuetCentre for Endocrinology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.
Silviu SbieraDivision of Endocrinology and Diabetes, Dept. of Medicine, University Hospital, University of Würzburg, Würzburg, Germany.
William M DrakeCentre for Endocrinology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.
Emanuel RognoniCentre for Cell Biology & Cutaneous Research, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Matthias KroissDivision of Endocrinology and Diabetes, Dept. of Medicine, University Hospital, University of Würzburg, Würzburg, Germany.
David T BreaultDivision of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Martin FassnachtDivision of Endocrinology and Diabetes, Dept. of Medicine, University Hospital, University of Würzburg, Würzburg, Germany.
Leonardo GuastiCentre for Endocrinology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.

Funding

Rosettes in Adrenal Development, Maintenance and DiseaseR01DK123694 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI David T Breault · 2019 to 2026
$5.6M
Barts Charity MGU0436BBSRC BB/V007246/1German Research Foundation 314061271MRC MR/S022155/1MRC MR/X021017/1National Institutes of Health Physician-Scientist Career Development R01DK123694NIDDK NIH HHS R01 DK123694Rosetrees Trust M355-F1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40035383
PMCPMC12187577

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.