ArticleJournal of frailty, sarcopenia and falls2025
Age-Related Differences in Adaptation of Lean Body Mass, Muscle Strength, and Performance Following 6 Weeks of Blood Flow Restriction Training in Young and Older Adults.
Article in Journal of frailty, sarcopenia and falls, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05615831 (The Impact of Exercise With Blood Flow Restriction), which is not on this map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Impact of Exercise With Blood Flow Restriction: Sex and Age Differences on Physical Performance, Muscle Hypertrophy, and Blood Biomarkers
Who cites it
3 citing papers in PubMed.
- Effectiveness of short-term cycling interventions in older adults: a randomized trial of hypoxic, blood flow restriction, and eccentric cycling.Scientific reports · 2025Trial
- Article
- Comparative analysis of high-intensity resistance training and blood flow restriction training on enhancing upper limb muscle strength and mass.Frontiers in physiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: The primary objective was to test the influence of age on lean body mass (LBM), muscle strength, and isokinetic performance adaptation following a 6-week blood-flow restriction training (BFRT) intervention. Methods: A total of 38 young adults (23.5±3.1) and 34 older adults (72.7±5.5) completed a 6-week BFRT program. Exercises were performed three times per week at 30% of 1-repetition maximums (1-RMs) and 60% of each limb's arterial occlusion pressure. Body composition was assessed using dual-energy X-ray absorptiometry, muscle strength was measured using 1-RMs, and muscular performance was measured using an isokinetic dynamometer. Results: A significant increase in LBM was observed in young adults (0.9±1.5kg; p<0.001) but not in older adults (0.3±1.3kg; p>0.05) following the intervention. Both age groups significantly improved 1-RMs for knee extension, knee flexion, and chest press, with the young group displaying greater improvements (all ps<0.001). A significant increase in knee flexion torque and power was observed in young adults (all ps<0.001) but not in older adults, while a significant difference between groups was observed (p<0.05). Conclusions: The results from our study suggest that young adults improve LBM and muscle performance following 6-weeks of BFRT, while older adults enhance performance, despite a lack of improvement in LBM. Clinicaltrials.gov ID: NCT05615831.
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Registered trials
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