ArticleRSC advances2025
A hybrid scaffold of modified human amniotic membrane with gelatine/dendrimer-protected silver nanoparticles for skin wound healing applications.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Development of alendronate-loaded 3D-printed PCL/LDH scaffolds for controlled drug delivery in bone tissue engineering.RSC advances · 2026Article
- Harnessing the Bio-Instructive Placental Extracellular Matrix: Structural Properties, Decellularization, and Applications in Regenerative Medicine.International journal of molecular sciences · 2026Review
- The Role of 3D Printing in Regenerative Medicine: A Game-Changer in Tissue Engineering.International journal of molecular sciences · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human amniotic membrane (hAM) is a biological material widely utilized to mimic the extracellular matrix in damaged skin. Despite its potential, clinical applications of hAM have been hindered by its poor mechanical properties. Furthermore, cryopreservation process used to store hAM could compromise its inherent bactericidal properties. This study explores an innovative approach by combining hAM with 2, 4, 6 and 8% w/v of gelatine (Gel) and incorporating 100, 500 and 1000 μL of poly(propylene imine) (PPI) dendrimer-protected silver nanoparticles (AgNPs) to create antibacterial-bolstered scaffolds using freeze-drying technique. Based on results, hAM/Gel2/S500 scaffold was identified as optimal specimen. It exhibited favorable properties, including an ultimate tensile strength of 16 kPa, an elastic modulus of 26.66 kPa, an elongation at break of 59.60%, an average pore size of 490 μm and a porosity of 52.93%.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.