ArticleIJU case reports2025
A case of papillary renal cell carcinoma with para-aortic lymph node metastasis that was completely resectable after treatment with combination therapy comprising lenvatinib and pembrolizumab and robot-assisted radical nephrectomy.
Article in IJU case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Achieving Complete Cytoreduction After Systemic Therapy for Stage IV Renal Carcinoma With Multicompartment Recurrence and Peritoneal Carcinomatosis: A Case Report.Case reports in oncological medicine · 2026Article
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7 authors.
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Abstract
Introduction: Combination therapy comprising immune checkpoint inhibitors and molecular targeted therapies can be effective for metastatic non-clear cell renal cell carcinoma. We describe a patient with metastatic papillary renal cell carcinoma that was completely pathologically resectable after combination treatment comprising lenvatinib and pembrolizumab and robot-assisted radical nephrectomy. Case presentation: A 35-year-old man was referred to our department for examination of a renal tumor that was diagnosed as left renal cell carcinoma with lymph node metastasis (cT3aN1M0). Because metastasis affected the renal artery, combination therapy comprising lenvatinib and pembrolizumab was initiated. After 6 months of treatment, the patient underwent robot-assisted radical nephrectomy. The pathological results indicated papillary renal cell carcinoma with no viable cells in the lymph nodes. Conclusion: Combination therapy comprising lenvatinib and pembrolizumab for unresectable papillary renal cell carcinoma may effectively allow radical resection and deferred cytoreductive nephrectomy.
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