ReviewRSC advances2025
Hydrazones, hydrazones-based coinage metal complexes, and their biological applications.
Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The trial behind it
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Who cites it
19 citing papers in PubMed.
- A Xanthene-Scaffold Fluorescent Probe for Dual-Mode Fluorescence-Colorimetric Detection of Hydrazine and its Application in Environmental Analysis.Journal of fluorescence · 2026Article
- Investigation of the In Vitro and In Silico Anticancer Potential of Novel 4-Arylthiazole-Hydrazone Derivatives.Chemical biology & drug design · 2026Article
- Dual Anticancer and Antibacterial Applications of Active Particle Aggregates Containing Metal Phthalocyanines in Dark.International journal of molecular sciences · 2026Article
- Monomeric Zn(II) and 3D polymeric Ag(I) complexes with a cationic s-triazine hydrazone-based ligand; synthesis, structure, coordination behavior and biological studies.Scientific reports · 2026Article
- Hydrazone-heterocyclic hybrids as promising anticancer agents: a comprehensive review.RSC advances · 2026Review
- N-sulfonylated indole hydrazone hybrid targeting Staphylococcus aureus with compelling antibiofilm and membrane-disrupting properties.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Dinuclear Copper(II) and Molybdenum(VI) Complexes of Bis-Tridentate Hydrazonylthiophene: Synthesis and Biochemical Evaluation.Chemistry & biodiversity · 2026Article
- Biological and thermal studies on imidazoline/dimethyl pentanedioate hybrids connected via a hydrazinylidene linker.Scientific reports · 2026Article
- Metal-free Minisci C-H alkylation of hydrazones using aldehydes: an unexpected route to hydrazone-containing pyrimidine derivatives.RSC advances · 2026Article
- Novel triphenylphosphonium-hydrazone salts: integrated experimental and computational insights into AChE inhibition and resistance-overcoming antimicrobial and antibiofilm potential.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Design, synthesis, and evaluation of novel triazole-based carbohydrazide derivatives with notable antioxidant activity: an integrated experimental and DFT study.BMC chemistry · 2026Article
- Spectroscopic, computational, and biological activity studies of bivalent metal complexes of (RSC advances · 2026Article
- Article
- Novel Triazole-Carbohydrazide hydrazones with dual antioxidant and antibacterial potential.Scientific reports · 2025Article
- Copper(II) Complexes of Selected Acylhydrazones as Potential Biological Agents.International journal of molecular sciences · 2025Article
- Synthesis, computational, biological activity and molecular docking study of CoScientific reports · 2025Article
- Catalyst-Free Assembly of δ-Lactam-Based Hydrazide-Hydrazone Compounds from 3-Arylglutaconic Anhydrides and Aldazines.International journal of molecular sciences · 2025Article
- Biological Activities of Etodolac-Based Hydrazone, Thiazolidinone and Triazole Derivatives on Breast Cancer Cell Lines MCF-7 and MDA-MB-231.Journal of biochemical and molecular toxicology · 2025Article
- Pharmacological Evaluation of Novel Hydrazide and Hydrazone Derivatives: Anti-Inflammatory and Analgesic Potential in Preclinical Models.Molecules (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydrazone-based compounds distinguished by their azomethine -NHN[double bond, length as m-dash]CH group and their respective coinage metal complexes have emerged as leading candidates in the search for effective anticancer and antibiotic agents. Because of their varied pharmacological potential and simplicity of synthesis, these compounds have been the subject of substantial research. Hydrazones exhibit versatile coordination chemistry, allowing for the formation of stable complexes with metals such as copper, silver, and gold. Hydrazone derivatives and their metal complexes demonstrate significant biological activities, displaying potent anticancer properties inducing apoptosis, inhibiting cell proliferation, and disrupting angiogenesis. Furthermore, they exhibit vigorous antibiotic activity by compromising microbial cell membranes and inhibiting essential enzymes. This review article highlights the versatility and effectiveness of hydrazone-based compounds and their coinage metal complexes reported for the last five years, underscoring their potential as next-generation diagnostic and therapeutic agents. Ongoing research focuses on optimizing these compounds for more excellent selectivity, potency, and biocompatibility, which is expected to advance their practical biological applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.