Evidence map›Paper›PMID 40034782›Full record

ArticlemedRxiv : the preprint server for health sciences2025

A Streamlined Point-of-Care CRISPR Test for Tuberculosis Detection Directly from Sputum.

Owen R S Dunkley, Alexandra G Bell, Nisha H Modi, Yujia Huang, Soleil Tseng, Robert Reiss, Naranjargal Daivaa, J Lucian Davis, Deninson Alejandro Vargas, Padmapriya Banada and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Owen R S DunkleyDepartment of Molecular Biology, Princeton University, Princeton New Jersey, 08544, USA.
Alexandra G BellDepartment of Molecular Biology, Princeton University, Princeton New Jersey, 08544, USA.
Nisha H ModiPublic Health Research Institute, Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, 07103, USA.
Yujia HuangDepartment of Molecular Biology, Princeton University, Princeton New Jersey, 08544, USA.
Soleil TsengDepartment of Molecular Biology, Princeton University, Princeton New Jersey, 08544, USA.
Robert ReissPublic Health Research Institute, Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, 07103, USA.
Naranjargal DaivaaPublic Health Research Institute, Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, 07103, USA.
J Lucian DavisDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, United States of America.
Deninson Alejandro VargasCentro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia.
Padmapriya BanadaPublic Health Research Institute, Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, 07103, USA.
Yingda L XiePublic Health Research Institute, Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, 07103, USA.
Cameron MyhrvoldDepartment of Molecular Biology, Princeton University, Princeton New Jersey, 08544, USA.

Funding

New Jersey Alliance for Clinical Translational Science: NJ ACTSUL1TR003017 · NCATS · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI PANETTIERI, REYNOLD ALEXANDER · 2019 to 2023
$28.9M
PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007388 · NIGMS · PRINCETON UNIVERSITY · PI CRISTEA, ILEANA M. · 1985 to 2022
$27.4M
Methods and Logic in Molecular Biology Training ProgramT32GM148739 · NIGMS · PRINCETON UNIVERSITY · PI Ileana M. Cristea · 2023 to 2026
$3.6M
Development of a highly-multiplexed CRISPR-based TB drug susceptibility testR01AI182281 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Cameron Amadeus Myhrvold, Yingda Linda Xie · 2024 to 2026
$2.2M
Development of a rapid multiplex CRISPR-based testing pathway for tuberculosis and COVID-19R21AI168808 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI BANADA, PADMAPRIYA, MYHRVOLD, CAMERON AMADEUS · 2022 to 2023
$438k
Mobile Health and Oral Testing to Optimize Tuberculosis Contact Tracing in ColombiaR21AI174129 · NIAID · YALE UNIVERSITY · PI DAVIS, JOHN LUCIAN · 2023 to 2024
$381k
NCATS NIH HHS UL1 TR003017NIAID NIH HHS R01 AI182281NIAID NIH HHS R21 AI168808NIAID NIH HHS R21 AI174129NIGMS NIH HHS T32 GM007388NIGMS NIH HHS T32 GM148739
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40034782
PMCPMC11875272

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.