ArticleJournal of Taibah University Medical Sciences2025
Article in Journal of Taibah University Medical Sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study assessed the inhibitory potential of proteins extracted from Methods: Crude proteins were extracted using common biological buffers (20 mM acetate, 20 mM phosphate and 20 mM Tris) at a ratio of 1:5 followed by 80 % ammonium sulfate precipitation, dialysis, and lyophilization. Then the lyophilized extracts were resolved on 15 % sodium dodecyl sulfate polyacrylamide electrophoresis (SDS-PAGE) gels. The Tris extract showing the maximum number of protein bands on the SDS gel was further assessed for inhibitory bioactivities. Specifically, the agar well diffusion method was performed to assess the inhibitory activities of phospholipase A2 (PLA2), protease, and α-amylase using 2 % egg yolk, 5 % skim milk and 1 % starch as substrates, respectively. Results: The Tris extract of seed proteins exhibited 19 % inhibition of snake venom PLA2 at a concentration of 125 μg/μL concentration, whereas no venom protease inhibition or antibacterial activity was observed at the highest concentrations analyzed. Significant antioxidant activity (44.9 %) was observed at 600 μg/μL, while α-amylase-enhancing activity in a concentration-dependent manner was noted. Conclusion: The results of this study demonstrated snake venom PLA2 neutralization, which is a major toxic enzyme present in snake venom, along with significant antioxidant properties. This study highlights the potential of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.