Evidence map›Paper›PMID 40034709›Full record

ReviewFrontiers in immunology2025

Research progress of extracellular vesicles in the pathogenesis of type IIIA chronic prostatitis.

Le Cheng, Peiyue Luo, Wei Li, Qi Chen, Lifeng Gan, Fangtao Zhang, Liying Zheng, Biao Qian

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Le ChengThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Peiyue LuoThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Wei LiThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Qi ChenThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Lifeng GanThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Fangtao ZhangThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Liying ZhengDepartment of Graduate, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.
Biao QianDepartment of Urology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic prostatitis is a prevalent urological condition that significantly impacts patients' quality of life. Advances in the study of Extracellular Vesicles (EV) have revealed their close involvement in the pathogenesis of prostatitis. This paper reviews the progress in understanding the role of EV in the pathogenesis of chronic prostatitis type IIIA, particularly their involvement in inflammatory responses, cell signaling, and interactions with immune cells. Additionally, it explores the potential applications of EV as drug delivery vehicles, including the targeted delivery of anti-inflammatory agents and immunomodulators, and highlights the challenges associated with developing exosome-based therapeutic strategies. In-depth research on EV holds promise for offering new insights into the diagnosis and treatment of inflammatory diseases.

Indexed as

Extracellular VesiclesProstatitisAnimalsChronic DiseaseExosomesHumansMaleSignal Transductionapplication potentialextracellular vesiclesinteractive functional modulationmolecular mechanismtype IIIA chronic prostatitis

Identifiers

PMID40034709
PMCPMC11873842

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.