ReviewCureus2025
Correlating Dose and Time of Prenatal Alcohol, Smoking, and Drug Exposure on Craniofacial Morphology: A Systematic Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this systematic review is to identify the dose and timing associated with the risk of in-utero substance exposure to craniofacial dysmorphia. This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, considering articles written in English up to March 2024. Cochrane, Medline, and Google Scholar databases were considered. After reading all eligible studies in full text, the two reviewers discussed their results and re-read those studies for which results differed in order to find a consensus. A total of 300 studies were extracted from the databases. Eleven articles were selected in the first screening, and one more article was included after the cursory screening. This study provides data on the prevalence of growth abnormalities, as well as facial and central nervous system (CNS) anomalies in children heavily exposed to teratogens in utero, based on an unselected sample from prospectively monitored pregnancies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.