ArticleJournal of Alzheimer's disease reports
Etiologies of rapidly progressive dementias: A systematic review and meta-analysis of causes in worldwide and Latin America.
Article in Journal of Alzheimer's disease reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Rapidly progressive dementia (RPD) is a group of neurological diseases, where three etiologies are particularly relevant: neurodegenerative, prion and autoimmune encephalitis (AIE) diseases. Objective: The aim of this study is to conduct a systematic review and meta-analysis of the frequency of these etiologies causing RPD in worldwide and Latin America (LatAm). Methods: A systematic review and meta-analysis were conducted. A bibliographic search of publications related to the etiologies of RPD was done. The etiologies, the timeframe definition (<1 year versus <2 years) and the study's place of origin were analyzed. Results: A total of 10 articles were selected for the analysis in this study (n = 1006 patients). Three studies were originated in LatAm cohorts (two from Argentina and one from Brazil). The global prevalence of RPD due to neurodegenerative disease was 23% CI95% [11%; 42%]; prion diseases, 16% CI95% [9%; 28%]; and AIE, 12% CI95% [6%; 22%]. Comparing each overall proportion of etiologies of LatAm versus non-LatAm there were statistically significant differences for AIE (25% versus 8%, respectively, Conclusions: From our results, approximately a half of the causes of RPD were due to neurodegenerative, prion, and AIE diseases. Future studies will be needed to analyze this issue both globally and regionally.
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