ArticleJournal of Alzheimer's disease reports
Protective effect of chlorogenic acid on cognitive impairment in rats with early Alzheimer's disease via Wnt signaling pathway.
Article in Journal of Alzheimer's disease reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Investigating the effects of chlorogenic acid on novel object recognition memory impairment, hyperlocomotion, and prefrontal BDNF expression in a sub-chronic ketamine-induced schizophrenia-like rat model.IBRO neuroscience reports · 2026Article
- Plant-mediated green nanoparticles: combining nanometal and biometabolite potential for Alzheimer's treatment.Biomedical engineering online · 2026Review
- Chlorogenic Acid: Characteristics, Neuroprotective Effects, and Potential Mechanisms.Current neuropharmacology · 2026Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chlorogenic acid (CGA) has neuroprotective properties associated with Alzheimer's disease (AD). However, the exact mechanism by which CGA prevents cognitive impairment in AD remains unclear. The purpose of this study was to investigate the protective effect of CGA on cognitive impairment in rats with early AD via the Wnt signaling pathway. Objective: To investigate the protective effect of CGA on cognitive impairment in an early AD rat model via the Wnt signaling pathway. Methods: Forty male rats were randomly divided into the control group (CON), AD group (AD), CGA 100 groups and CGA 150 groups with 10 rats in each group. In addition to CON group, the other three groups of rats were injected with 10 μL Aβ Results: CGA reduced the escape latency of Aβ Conclusions: CGA can protect the cognitive impairment of early AD rats via Wnt signaling pathway.
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Registered trials
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