ArticleClinical kidney journal2024
Kidney function and bone mineral density in chronic kidney disease patients.
Article in Clinical kidney journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07171216 (The Effect of REgulation of PArathyroId hoRmone in Patients With Chronic Kidney Disease to Investigate the Change in Bone Mineral Density), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of REgulation of PArathyroId hoRmone in Patients With Chronic Kidney Disease to Investigate the Change in Bone Mineral Density (Biskjoldbruskkirtelhormon og knogletæthed Hos Patienter Med Kronisk Nyresygdom)
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global and regional prevalence of osteoporosis in kidney transplant recipients: a systematic review and meta-analysis.Clinical and experimental medicine · 2025Pooled it
- Accelerated bone loss increases osteoporosis and fracture risk in moderate to severe chronic kidney disease.Renal failure · 2026Article
- High prevalence of sarcopenia, osteoporosis and osteosarcopenia in patients with chronic kidney disease compared with healthy controls.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Article
- Impact of fluorosis on mineral bone disorders in CKDu populations: a cross-sectional study.BMC nephrology · 2025Article
- Subgroup-Specific Osteoporosis Risk in Chronic Kidney Disease: Insights from a Nationwide Korean Cohort.Biomedicines · 2025Article
- Association between dietary fiber intake and total bone mineral density in adolescents: A cross-sectional analysis of the NHANES 2011-2018.Science progressArticle
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Bone mineral density (BMD) predicts fracture risk in patients with chronic kidney disease (CKD) and in the general population. However, few studies have investigated risk factors for bone loss in patients with CKD. The aim of this study was to investigate whether renal function is associated with the rate of BMD decline. Methods: A prospective cohort study included 1006 patients with CKD stages 2-4 between 2011 and 2016. BMD was measured using dual-energy X-ray absorptiometry at baseline and 4 years. The eGFR was measured 2-6 times during the 4-year follow-up. We analyzed the decline in bone mineral density according to CKD stage and further compared the rate of BMD decline according to eGFR trajectories at each stage. Results: Advanced CKD stage was associated with a faster rate of decline in total hip BMD [stage 2 -0.23, stage 3A -0.39, stage 3B -0.80, stage 4 -1.23% change/year in men ( Conclusions: Advanced CKD stage and accelerated decline in renal function were associated with rapid BMD decline in non-dialysis patients with CKD.
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Registered trials
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