Evidence map›Paper›PMID 40034432›Full record

ArticleResearch square2025

What do we actually want to experience? A computational metric for assessing reward values.

Christian E Waugh, Adam P Porth, Xuanyu Fang, L Paul Sands, Kenneth T Kishida

Registry-linked trialAbstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07005817 (Ameliorating Social Isolation), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07005817 naenrolling by invitationnot on this map

Ameliorating Social Isolation: Identifying Factors That Impede or Facilitate Health-related Social Behavior Change

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2025 to 2027Enrolled1,900ConditionsSocial Isolation, LonelinessArmsExperimental Health Communication, Simulated Social Media Platform Only
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christian E WaughDepartment of Psychology, Wake Forest University, 1834 Wake Forest Rd. Winston Salem, NC USA.
Adam P PorthDepartment of Psychology, Wake Forest University, 1834 Wake Forest Rd. Winston Salem, NC USA.
Xuanyu FangDepartment of Psychology, Wake Forest University, 1834 Wake Forest Rd. Winston Salem, NC USA.
L Paul SandsDepartment of Physiology and Pharmacology, Wake Forest School of Medicine, Winston Salem, NC USA.
Kenneth T KishidaDepartment of Physiology and Pharmacology, Wake Forest School of Medicine, Winston Salem, NC USA.

Funding

Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
Dopaminergic encoding of counterfactual information in human striatumR01NS092701 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI MONTAGUE, P READ · 2015 to 2019
$2.6M
Neuro-computational Approach to Determine a Neurochemical Basis of Mood and DepressionR01MH121099 · NIMH · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KISHIDA, KENNETH TUCKER · 2019 to 2023
$1.9M
Real-time neurochemical encoding of reward- and punishment-prediction errors and associated subjective experiences in humansR01DA048096 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KISHIDA, KENNETH TUCKER · 2019 to 2023
$1.7M
NCATS NIH HHS UL1 TR000142NIDA NIH HHS R01 DA048096NIMH NIH HHS R01 MH121099NINDS NIH HHS R01 NS092701
6 · The paper itself

Abstract

People's motivation to have different experiences is predicated on how much they find those experiences rewarding or not, and these reward values are not always fully accessible to our consciousness. In two studies, we demonstrate that using a combination of reinforcement learning (RL) paradigms and computational modeling, we can measure computationally inferred reward values (cRV) of experiences, which do not rely on conscious self-report. Consistent with motivational reward theory, convenience samples of participants exhibited higher cRV (greater reward value of that experience) to viewing positive vs. negative images (subject pool; Study 1) and to viewing more vs. less attractive faces (online sample; Study 2). Further, these cRVs were sensitive to context (familiarity vs. novelty of images, Study 1) and to individual differences (attraction preference, Study 2). Lastly, although cRVs were mildly correlated with explicit self-report values, which demonstrates their validity, they were better predictors of behavior than were the explicit values, which suggests that cRVs are capturing reward processes that are not represented by explicit value judgments. This method of measuring cRV holds great promise for understanding the motivation driving people's choices of a variety of experiences across a wide array of fields of study.

Indexed as

computationalmotivationreinforcement learningreward

Identifiers

PMID40034432
PMCPMC11875320

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.