Evidence map›Paper›PMID 40034412›Full record

ReviewBioactive materials2025

Red blood cells-derived components as biomimetic functional materials: Matching versatile delivery strategies based on structure and function.

Hangbing Liu, Yi Li, Yuli Wang, Liying Zhang, Xiaoqing Liang, Chunsheng Gao, Yang Yang

Abstract readReview
In one paragraph

Review in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hangbing LiuBeijing Institute of Pharmacology and Toxicology, 100850, Beijing, People's Republic of China.
Yi LiBeijing Institute of Pharmacology and Toxicology, 100850, Beijing, People's Republic of China.
Yuli WangBeijing Institute of Pharmacology and Toxicology, 100850, Beijing, People's Republic of China.
Liying ZhangBeijing Institute of Pharmacology and Toxicology, 100850, Beijing, People's Republic of China.
Xiaoqing LiangBeijing Institute of Pharmacology and Toxicology, 100850, Beijing, People's Republic of China.
Chunsheng GaoBeijing Institute of Pharmacology and Toxicology, 100850, Beijing, People's Republic of China.
Yang YangBeijing Institute of Pharmacology and Toxicology, 100850, Beijing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Red blood cells (RBCs), often referred to as "intelligent delivery systems", can serve as biological or hybrid drug carriers due to their inherent advantages and characteristics. This innovative approach has the potential to enhance biocompatibility, pharmacokinetics, and provide targeting properties for drugs. By leveraging the unique structure and contents of RBCs, drug-loading pathways can be meticulously designed to align with these distinctive features. This review article primarily discusses the drug delivery strategies and their applications that are informed by the structural and functional properties of the main components of RBCs, including living RBCs, membranes, hollow RBCs, and hemoglobin. Overall, this review article would assist efforts to make better decisions on optimization and rational utilization of RBCs derivatives-based drug delivery strategies for the future direction in clinical translation.

Indexed as

BiomimeticCell membraneDrug deliveryErythrocyte ghostsHemoglobinRed blood cells derivatives

Identifiers

PMID40034412
PMCPMC11872572

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.