Evidence map›Paper›PMID 40034359›Full record

ArticleJournal of Alzheimer's disease reports2024

The association between activities and cognitive health: Stratified analysis by

Yeonjung Jane Lee, Ernest Gonzales, Yanyan Wu, Kathryn L Braun, Peter Martin, Bradley Willcox, Ross Andel

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Prosocial helping behaviors attenuate accelerated cognitive decline driven by APOE ε4.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yeonjung Jane LeeDepartment of Social Work, Thompson School of Social Work & Public Health, University of Hawai'i at Mānoa, Honolulu, HI, USA.ORCID https://orcid.org/0000-0001-6406-8950
Ernest GonzalesThe Center for Health and Aging Innovation, New York University Silver School of Social Work, New York, NY, USA.
Yanyan WuOffice of Public Health Studies, Thompson School of Social Work & Public Health, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Kathryn L BraunOffice of Public Health Studies, Thompson School of Social Work & Public Health, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Peter MartinHuman Development and Family Studies, Iowa State University, Ames, IA, USA.
Bradley WillcoxDepartment of Geriatric Medicine, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Ross AndelEdson College of Nursing and Health Innovation, Arizona State University, Phoenix, AZ, USA.

Funding

The Role of gp120 on Cardiovascular Disease in People Living with HIVU54MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI Benjamin C. Fogelgren · 2017 to 2026
$59.5M
Tracking and Evaluation CoreU54GM138062 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI SY, ANGELA U · 2021 to 2025
$15.5M
Productive and Leisure Activities and Cognition in Later LifeP20GM125526 · NIGMS · KUAKINI MEDICAL CENTER · PI WILLCOX, BRADLEY JOHN · 2019 to 2023
$12.0M
NIGMS NIH HHS P20 GM125526NIGMS NIH HHS U54 GM138062NIMHD NIH HHS U54 MD007601
6 · The paper itself

Abstract

Background: Despite the growing evidence on the modifiable and genetic factors associated with cognitive health, little is known about the role of the apolipoprotein E ( Objective: This study fills a gap of knowledge by examining the associations among employment, civic engagement, and leisure activities and cognitive health by the presence of Methods: Using pooled data from the Health and Retirement Study (HRS) Psychosocial and Lifestyle Questionnaires (2010-2016) and the HRS data on Results: Among all participants, employment, low or high-intensity volunteering, and cognitive/social leisure activities were associated with higher levels of cognitive functioning. The presence of at least one ε4 allele was related to poorer cognitive functioning at the follow-up time point. Among people without the Conclusions: We found that employment, civic engagement, and leisure activities all contribute to cognitive health, although the benefits may be restricted to low-intensity volunteering and cognitive/physical leisure activities among individuals with at least one

Indexed as

Alzheimer's diseaseApolipoprotein Ecognitionemploymentrecreationvolunteer

Identifiers

PMID40034359
PMCPMC11863737

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.