ArticleHeliyon2025
Effect of biotin supplementation and swimming training on oxidative stress and testicular function in male rats.
Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Effects ofAdvances in pharmacological and pharmaceutical sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress (OS) affects testicular function and is a significant cause of sperm cell dysfunction in males. The development of male infertility is closely linked to a sedentary lifestyle and diet. This study aimed to characterize the protective effects of biotin supplementation (BS) and swimming training (ST) on OS markers in the reproductive system of male rats. Forty male rats (200-250 g) were randomly assigned to four groups (n = 10 per group) and treated for 28 days as follows: control, BS (this group received BS through oral gavage), ST, and BS + ST groups. Our results showed that glutathione (GSH) levels significantly increased in the BS, ST (p < 0.05), and BS + ST (p < 0.01) groups, whereas malondialdehyde (MDA) levels significantly decreased in these experimental groups (p < 0.05 for all). Additionally, compared to the controls, there was a significant increase (p < 0.05) in blood levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T), and
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Registered trials
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