Evidence map›Paper›PMID 40034193›Full record

ArticleJournal of the American College of Emergency Physicians open2025

Emergency Department Placed Central Lines for Trauma Patients: A Retrospective Case-Control Study on Central Line-Associated Blood Stream Infection Risk From Central Lines Placed Emergently in the Emergency Department.

Larissa Epstein, Jeffry Nahmias, Sebastian Schubl, Kenji Inaba, Kazuhide Matsushima, Michael Lekawa, Matthew Dolich, Areg Grigorian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American College of Emergency Physicians open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Larissa EpsteinDepartment of Surgery, University of Southern California, Los Angeles, California, USA.
Jeffry NahmiasDivision of Trauma, Burns and Surgical Critical Care, Department of Surgery, University of California, Irvine Medical Center, Orange, California, USA.
Sebastian SchublDivision of Trauma, Burns and Surgical Critical Care, Department of Surgery, University of California, Irvine Medical Center, Orange, California, USA.
Kenji InabaDepartment of Surgery, University of Southern California, Los Angeles, California, USA.
Kazuhide MatsushimaDepartment of Surgery, University of Southern California, Los Angeles, California, USA.
Michael LekawaDivision of Trauma, Burns and Surgical Critical Care, Department of Surgery, University of California, Irvine Medical Center, Orange, California, USA.
Matthew DolichDivision of Trauma, Burns and Surgical Critical Care, Department of Surgery, University of California, Irvine Medical Center, Orange, California, USA.
Areg GrigorianDivision of Trauma, Burns and Surgical Critical Care, Department of Surgery, University of California, Irvine Medical Center, Orange, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Emergent central line (CL) insertion may be associated with a higher risk of central line-associated blood stream infection (CLABSI). We hypothesized that CLs placed emergently within 2 hours of arrival to the emergency department (ED) for critical trauma patients are associated with a higher risk of CLABSI compared with CLs placed outside the ED. We additionally hypothesized that femoral ED-CLs are associated with a higher risk of CLABSI compared with internal jugular (IJ) vein ED-CLs. Methods: The 2017-2019 Trauma Quality Improvement Program database was queried for critical trauma patients admitted to the intensive care unit or operating suite from the ED who underwent CL insertion. Patients who were transferred, died < 72 hours, or hospitalized <2 days were excluded. A total of 27,981 patients met inclusion criteria and 169 of these patients met criteria for a CLABSI. Patients receiving an ED-CL within 2 hours of arrival were compared with patients receiving a CL outside of the ED (non-ED-CL). We performed a subanalysis of only ED-CL patients for risk of CLABSI dependent on insertion site. A multivariable logistic regression analysis was performed. Results: Of 27,981 patients, 7908 (28.3%) received an ED-CL mostly in the subclavian vein (51.5%). After adjusting for risk factors, ED-CL patients had a similar risk of CLABSI (odds ratio [OR], 0.75; CI, 0.51-1.11; Conclusion: Insertion of ED-CLs within 2 hours of arrival is not associated with a higher risk of CLABSI compared with insertion of a non-ED-CLs. The subclavian vein is the most common site for emergent CL insertion in the ED. For ED-CLs, the subclavian line is associated with the lowest risk of CLABSI and should be considered the optimal site for insertion in critically ill trauma patients with no known history of chronic kidney disease.

Indexed as

central linecentral venous catheterCLABSIemergency department

Identifiers

PMID40034193
PMCPMC11874560

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.