ArticleNeuropsychiatric disease and treatment2025
Understanding Relapse in Bipolar Disorder at a Tertiary Mental Health Facility in Uganda.
Article in Neuropsychiatric disease and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Bipolar disorder (BD) is a chronic psychiatric condition characterized by recurrent episodes of mania, hypomania, and depression, affecting approximately 1 in 150 adults globally. BD contributes significantly to disability and years of life lost, with a notable prevalence in Africa. The high relapse rates in BD, exacerbated by limited mental health resources and underdiagnosis, highlight the need for targeted interventions. This study explores the factors contributing to relapse among BD patients at Butabika National Referral Mental Hospital, Uganda, a crucial mental health facility in the region. Methods: This cross-sectional qualitative study was conducted at Butabika National Referral Mental Hospital. Adult patients aged 18-65, diagnosed with BD and experiencing relapse after treatment, were included. Data were collected through purposive sampling, focusing on obtaining detailed personal accounts from approximately 15 participants until data saturation was achieved. Thematic analysis identified key themes and subthemes related to relapse factors. Results: Five major themes emerged: treatment adherence, psychosocial factors, cultural beliefs, economic challenges, and coping mechanisms. Non-adherence to medication, driven by side effects, forgetfulness, and financial constraints, was a significant relapse factor. Psychosocial stressors, such as life events and social isolation, alongside stigma and cultural beliefs in traditional healing, further complicated relapse patterns. Economic hardships affected medication access and treatment consistency. Supportive social networks and psychoeducation emerged as crucial for effective management and relapse prevention. Conclusion: Addressing medication adherence, psychosocial stressors, cultural beliefs, and economic barriers through a holistic approach integrating medical treatment with psychoeducation and support systems is essential for improving patient outcomes and reducing relapse rates in this setting. Therefore, the effective management of bipolar disorder at Butabika National Referral Mental Hospital requires a complex interplay between biological, psychological, and social factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.