Evidence map›Paper›PMID 40034101›Full record

ArticleJournal of neuroendovascular therapy2025

Quantitative Evaluation of Ischemic Core Volume in GE's CT Perfusion Imaging Analysis Software and Its Relationship to Alberta Stroke Program Early CT Score.

Kenta Nakanishi, Takanori Sano, Kengo Iwaki, Kazuto Kobayashi, Youhei Kawaguchi, Atsushi Kobayashi, Akira Kamaya, Fumitaka Miya

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroendovascular therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kenta NakanishiRadiological Technology Section, Department of Medical Technology, Japanese Red Cross Ise Hospital, Ise, Mie, Japan.
Takanori SanoDepartment of Neurosurgery, Mie Prefectural General Medical Center, Yokkaichi, Mie, Japan.
Kengo IwakiRadiological Technology Section, Department of Medical Technology, Japanese Red Cross Ise Hospital, Ise, Mie, Japan.
Kazuto KobayashiDepartment of Neurology, Japanese Red Cross Ise Hospital, Ise, Mie, Japan.
Youhei KawaguchiRadiological Technology Section, Department of Medical Technology, Japanese Red Cross Ise Hospital, Ise, Mie, Japan.
Atsushi KobayashiRadiological Technology Section, Department of Medical Technology, Japanese Red Cross Ise Hospital, Ise, Mie, Japan.
Akira KamayaRadiological Technology Section, Department of Medical Technology, Japanese Red Cross Ise Hospital, Ise, Mie, Japan.
Fumitaka MiyaDepartment of Neurosurgery, Japanese Red Cross Ise Hospital, Ise, Mie, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Computed tomography (CT) and magnetic resonance imaging of cerebral perfusion are useful in determining the indication of mechanical thrombectomy (MT) for acute ischemic stroke. RAPID (iSchemaView, Menlo Park, CA, USA) is the most common software for analyzing brain perfusion images worldwide, but various other software are also available. The optimal threshold value for each software is different, and each has its characteristics. This study investigated the relationship between the quantitative evaluation of ischemic core volume (ICV) and the Alberta Stroke Program Early CT Score (ASPECTS) using CT Perfusion 4D (GE Healthcare Inc., Milwaukee, WI, USA), a software used in our hospital. Methods: Among patients who underwent MT between April 2015 and February 2023, those with modified Rankin Scale: 0-2, obstruction by embolic mechanism, and thrombolysis in cerebral infarction: 2b or higher were selected retrospectively. Patients with middle cerebral artery M1 segment (M1) and internal carotid artery (ICA) occlusions (90 and 46 patients) were included. We quantitatively analyzed ICV at relative cerebral blood flow (rCBF) <20% and cerebral blood volume (CBV) <1 mL/100 g and evaluated the relationship with ASPECTS scores in 3 groups: M1 + ICA, M1, and ICA occlusion groups. Results: The median ICV was rCBF <20%: 44.7 cm Conclusion: The quantitative evaluation of ICV at rCBF <20% and CBV <1 mL/100 g was negatively correlated with the ASPECTS score in GE's CT Perfusion imaging analysis software.

Indexed as

Alberta Stroke Program Early CT ScoreCT Perfusionischemic core volume

Identifiers

PMID40034101
PMCPMC11873743

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.