Evidence map›Paper›PMID 40034061›Full record

ArticleAnnals of medicine2025

C-reactive protein to albumin ratio and Glasgow Coma Scale score as the predictors for weaning outcomes in traumatic brain injury.

Jiaxuan Zeng, Jiazhuo Liu, Yin Lu, Jiahui Fu, Dong Han, Jiali Chen, Zhimin Zou, Qin Li, Kun Zhang, Hongping Tan and 4 more

Abstract read
In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jiaxuan ZengDepartment of Treatment Center for Traumatic Injuries, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.ORCID 0009-0007-4722-7930
Jiazhuo LiuDepartment of Treatment Center for Traumatic Injuries, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.
Yin LuDepartment of Treatment Center for Traumatic Injuries, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.
Jiahui FuDepartment of Treatment Center for Traumatic Injuries, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.
Dong HanDepartment of Quality Control and Evaluation, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.
Jiali ChenDepartment of Treatment Center for Traumatic Injuries, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.
Zhimin ZouDepartment of Treatment Center for Traumatic Injuries, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.
Qin LiDepartment of Treatment Center for Traumatic Injuries, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.
Kun ZhangDepartment of Treatment Center for Traumatic Injuries, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.
Hongping TanThe Eighth Department of Neurosurgery, Guangdong Sanjiu Brain Hospital, Guangzhou, China.
Wenzhong YuDepartment of Emergency Medicine, Yunan People's Hospital, Yunfu, China.
Xiucai WeiDepartment of Treatment Center for Traumatic Injuries, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.
Zhengtao GuDepartment of Treatment Center for Traumatic Injuries, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.
Li LiDepartment of Treatment Center for Traumatic Injuries, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0001-5889-8667

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify the prognostic value of C-reactive protein to albumin ratio (CRP/ALB, CAR) and Glasgow Coma Scale (GCS) score in the weaning outcomes of mechanical ventilation (MV) in patients with traumatic brain injury (TBI).

methodsMedical records of patients with TBI who were hospitalized at The Third Affiliated Hospital of Southern Medical University between January 2018 and September 2023 were collected and analysed. The patients were divided into the weaning success group and the weaning failure group. Data from the two groups were analysed to assess the predictive value of CAR and GCS score on weaning outcomes.

resultsCAR was an independent risk factor for weaning failure (

conclusionsTBI patients with higher CAR and lower GCS score were more likely to experience weaning failure, which can provide reliable guidance for patients with TBI to leave the ventilator.

Indexed as

Brain Injuries, TraumaticC-Reactive ProteinSerum AlbuminVentilator WeaningAdultAgedBiomarkersFemaleGlasgow Coma ScaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRespiration, ArtificialRetrospective StudiesBiomarkersC-Reactive ProteinSerum Albuminacute lung injury (ALI)C-reactive protein to albumin ratio (CAR)Glasgow Coma Scale (GCS)mechanical ventilation (MV)Traumatic brain injury (TBI)

Identifiers

PMID40034061
PMCPMC11881653

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.