SynthesisEchocardiography (Mount Kisco, N.Y.)2025
Echocardiographic Parameters of Right Ventricular Size and Function Associated With Right Heart Failure After Durable Left Ventricular Assist Device Implantation-A Systematic Review and Meta-Analysis.
Synthesis in Echocardiography (Mount Kisco, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Ventricular Strain Predicts the Risk of Right Heart Failure After Durable Left Ventricular Assist Device Implantation.JACC. Advances · 2026Article
- From novice to expert: the reproducibility of 3D echocardiographic right ventricular assessment in heart failure patients.Frontiers in cardiovascular medicine · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLate-onset Right Ventricular (RV) failure is an established complication of Durable Left-Ventricular Assist Device (D-LVAD) implantation. Transthoracic echocardiography (TTE) remains the primary imaging modality for serial monitoring in this population, but its interpretation remains challenging due to device-related changes in RV size and function and a lack of guidelines addressing this impact. This study aims to examine the diagnostic and prognostic utility of TTE parameters of RV size and function in the detection of late-onset RV failure post-implantation. METHODS AND
resultsA systematic literature search of medical databases was performed to identify all relevant studies assessing TTE parameters in adult patients with D-LVADs (January 2003-August 2023; English only). Of the 350 studies identified, nine studies with a pooled cohort of 627 patients and three studies with a pooled cohort of 175 patients (40 Cases and 135 controls) were meta-analyzed across a range of structural and functional TTE parameters. Compared to World Alliance Societies of Echocardiography (WASE) reference values, this population had dilated RV size (as quantified by RVEDD) and reduced systolic function (as quantified by TAPSE, RVFAC, and RVEF). TAPSE was positively associated with the non-RVF group, while RVEDD was negatively associated with the non-RVF group.
conclusionsBased on the available studies, there was baseline RV dilatation and reduced systolic function in patients with D-LVADs. Additionally, TAPSE and RVEDD demonstrated a statistically significant association with the development of RVF post-implantation, indicating a potential role as prognostic markers. Further studies should also be conducted to establish post-implantation TTE reference values.
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