Evidence map›Paper›PMID 40033903›Full record

ArticleAustralian veterinary journal2025

Early-onset muscle weakness syndrome (MW) in an Australian Holstein calf.

M G Ciacia, A J Phipps

Abstract readCase Reports
In one paragraph

Article in Australian veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

M G CiaciaSchool of Agricultural, Environmental and Veterinary Sciences, Faculty of Science and Health, Charles Sturt University, Wagga Wagga, New South Wales, Australia.
A J PhippsRochester Veterinary Practice, Rochester, Victoria, Australia.ORCID https://orcid.org/0000-0003-3029-177X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early-onset muscle weakness syndrome (MW) is a recessive genetic disorder known to affect Holstein cattle. This report describes the clinical findings in an Australian Holstein calf diagnosed with MW. The calf initially presented for examination at a dairy farm at 3 days of age, being recumbent since birth but able to stand with assistance. A presumptive diagnosis of traumatic injury was made at first. However, the calf was re-examined multiple times due to ongoing intermittent episodes of recumbency, prompting further diagnostic investigation. Given the non-specific nature of the clinical and laboratory findings, a presumptive diagnosis of MW was made after reviewing the calf's breeding pedigree. A definitive diagnosis, however, required genotype testing. To the authors knowledge, this case report represents the first peer-reviewed manuscript to describe the clinical presentation of MW in an Australian Holstein calf.

Indexed as

Cattle DiseasesMuscle WeaknessAnimalsAnimals, NewbornAustraliaCattleFemaleMalePedigreecalf recumbencyearly‐onset muscle weakness syndromeHolsteinrecessive genetic disorder

Identifiers

PMID40033903
PMCPMC12050139

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.