Evidence map›Paper›PMID 40033876›Full record

ArticleJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]2025

A Personalized 4D Workflow for the Manufacturing of Functional and Removable Esthetic Devices: A Technical Report.

Mauro Merli, Luca Aquilanti, Alessio Casucci, Michele Nieri, Giorgia Mariotti, Marco Merli, Giorgio Rappelli

Abstract read
In one paragraph

Article in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mauro MerliDepartment of Clinical Specialistic and Dental Sciences, Polytechnic University of Marche, Ancona, Italy.
Luca AquilantiDepartment of Clinical Specialistic and Dental Sciences, Polytechnic University of Marche, Ancona, Italy.ORCID https://orcid.org/0000-0003-1079-8565
Alessio CasucciDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.
Michele NieriDepartment of Clinical and Experimental Medicine, University of Florence, Florence, Italy.
Giorgia MariottiClinica Merli, Rimini, Italy.
Marco MerliClinica Merli, Rimini, Italy.
Giorgio RappelliDepartment of Clinical Specialistic and Dental Sciences, Polytechnic University of Marche, Ancona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis technical report describes a fully digital workflow for the manufacturing of a functional removable esthetic device (FRED) that addresses multiple clinical scenarios before prosthetic rehabilitation. The proposed method integrates advanced digital tools to achieve functional and esthetic outcomes while ensuring reversibility and patient comfort. CLINICAL CONSIDERATIONS: The workflow includes intraoral and facial scanning, jaw motion tracking, and CAD/CAM technology to create a 4D virtual patient. This allows for a precise recording of the maxillomandibular relationship and facilitates the determination of the comfort position to establish a new occlusal vertical dimension (OVD). FRED is a custom-designed, removable, tooth-colored device manufactured to provide temporary functional support, esthetic preview, catering to different clinical scenarios, including tooth wear, occlusal trauma, and periodontal conditions.

conclusionsThis technique combines digital and traditional prosthetic principles into a patient-centered, adaptable workflow, allowing precise, non-invasive, and dynamic evaluation of OVD modifications. By integrating digital recording, facial scanning, and CAD/CAM fabrication, it enhances function, esthetics, and patient comfort. CLINICAL SIGNIFICANCE: This technique highlights the synergy of digital innovation and prosthetic principles, enhancing diagnostic capabilities and treatment predictability. The patient-centered design supports functional stability and esthetic outcomes, making it a valuable tool in modern prosthetic dentistry.

Indexed as

Computer-Aided DesignDental Prosthesis DesignEsthetics, DentalWorkflowHumans4D virtual patientdiagnostic esthetic devicejaw motion trackingmaxillomandibular relationshipocclusal vertical dimensionrest position

Identifiers

PMID40033876
PMCPMC12159782

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.