Evidence map›Paper›PMID 40033668›Full record

ArticleAnnals of transplantation2025

Herbal Medicine Use Among Transplant Recipients in Saudi Arabia: Prevalence and Risk Awareness.

Bassem A Almalki, Fawaz M Alotaibi, Mohammed Aldholmi, Yousef S Alqarni, Sawsan M Kurdi, Mohammed M Alsultan, Wafa A Alzlaiq, Mansour M Alotaibi, Noor M Alashi, Fatimah S Alzahrani and 10 more

Abstract read
In one paragraph

Article in Annals of transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Bassem A AlmalkiDepartment of Pharmacy Practice, Imam Abdulrahman Bin Faisal University, King Faisal, Dammam, Saudi Arabia.
Fawaz M AlotaibiDepartment of Pharmacy Practice, Imam Abdulrahman Bin Faisal University, King Faisal, Dammam, Saudi Arabia.
Mohammed AldholmiDepartment of Natural Products, Imam Abdulrahman Bin Faisal University, King Faisal, Dammam, Saudi Arabia.ORCID 0000-0003-3270-0338
Yousef S AlqarniDepartment of Pharmacy Practice, Imam Abdulrahman Bin Faisal University, King Faisal, Dammam, Saudi Arabia.
Sawsan M KurdiDepartment of Pharmacy Practice, College of Clinical Pharmacy, King Faisal University, Dammam, Saudi Arabia.
Mohammed M AlsultanDepartment of Pharmacy Practice, Imam Abdulrahman Bin Faisal University, King Faisal, Dammam, Saudi Arabia.ORCID 0000-0002-9578-9790
Wafa A AlzlaiqDepartment of Pharmacy Practice, Imam Abdulrahman Bin Faisal University, King Faisal, Dammam, Saudi Arabia.
Mansour M AlotaibiDepartment of Pharmacy Practice, College of Clinical Pharmacy, King Faisal University, Alhofuf, Saudi Arabia.
Noor M AlashiPharmaceutical Care Services, King Fahad Specialist Hospital, Dammam, Saudi Arabia.
Fatimah S AlzahraniPharmaceutical Care Services, King Fahad Specialist Hospital, Dammam, Saudi Arabia.
Nouf E AlotaibiDepartment of Pharmacy Practice, Umm Al-Qura University, Makkah Al-Mukarramah, Saudi Arabia.ORCID 0000-0001-7029-3089
Mohamed A AlbekeryDepartment of Pharmacy Practice, King Faisal University, Alhofuf, Saudi Arabia.ORCID 0000-0001-8472-3043
Sarah A AlbilalPharmaceutical Care Services, King Abdulaziz Medical City, Riyadh, Saudi Arabia.ORCID 0000-0002-7793-4237
Khawla M KahtaniPharmaceutical Care Services, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Mohammed Abdelgawad GafarDepartment of Adult Transplant Nephrology, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Sahar M Al-MowainaPharmaceutical Care Services, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Ahmed K AlalawiDepartment of Pharmacy Practice, Imam Abdulrahman Bin Faisal University, King Faisal, Dammam, Saudi Arabia.
Abdullah A AlshehabDepartment of Pharmacy Practice, Imam Abdulrahman Bin Faisal University, King Faisal, Dammam, Saudi Arabia.
Ahmed J AljasemDepartment of Pharmacy Practice, Imam Abdulrahman Bin Faisal University, King Faisal, Dammam, Saudi Arabia.
Abdulkareem M AlbekairyDepartment of Pharmacy Practice, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Herbal medicine is commonly used in Saudi Arabia, and is widely viewed as natural and safe. However, its use among transplant recipients poses risks due to interactions with immunosuppressive therapies. This study explores herbal medicine use, knowledge, and attitudes among Saudi transplant recipients. MATERIAL AND METHODS A cross-sectional study of 203 transplant recipients from multiple clinics in Saudi Arabia was conducted using a structured questionnaire to assess demographics, herbal supplement use, awareness of risks, and attitudes. Statistical analyses compared users and non-users of herbal supplements. RESULTS Post-transplant herbal supplement use decreased significantly (44.3% to 19.2%, p=0.0001). Many relied on unreliable sources like friends or the internet, and 54.24% of reported supplements posed interaction risks with immunosuppressive drugs. Participants aware of these risks were significantly less likely to use herbal supplements (15% vs 88%, p=0.0007). Alarmingly, 81.1% received no pre-transplant education, and 70.4% received no post-transplant care, despite 81% desiring guidance from healthcare providers. CONCLUSIONS Herbal supplement use among transplant recipients in Saudi Arabia is prevalent and risky due to potential drug interactions. Most patients lack education about these risks, underscoring the need for improved healthcare education.

Indexed as

Dietary SupplementsHealth Knowledge, Attitudes, PracticeHerbal MedicinePhytotherapyTransplant RecipientsAdultAgedCross-Sectional StudiesFemaleHerb-Drug InteractionsHumansImmunosuppressive AgentsMaleMiddle AgedPrevalenceSaudi ArabiaImmunosuppressive Agents

Identifiers

PMID40033668
PMCPMC11889984

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.