Evidence map›Paper›PMID 40033654›Full record

ArticleBalkan medical journal2025

Burden of Substance Use Disorders in the Middle East and North Africa from 1990 to 2019.

Seyed Reza Darijani, Homa Seyedmirzaei, Amin Nakhostin-Ansari, Iman Menbari-Oskouie, Amirhossein Ghaseminejad-Raeini, Hadis Nasoori, Amir Hossein Memari, Shahin Akhondzadeh

Abstract read
In one paragraph

Article in Balkan medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Observational
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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seyed Reza DarijaniSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-9956-9787
Homa SeyedmirzaeiOccupational Sleep Research Center, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-7799-9332
Amin Nakhostin-AnsariNeuromusculoskeletal Research Center, Iran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-1113-9257
Iman Menbari-OskouieUrology Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-5511-1512
Amirhossein Ghaseminejad-RaeiniSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-4322-0236
Hadis NasooriFaculty of Pharmacy, Tehran University of Medical Sciences, Islamic Azad University, Tehran, Iran.ORCID 0000-0003-0348-3768
Amir Hossein MemariSport Medicine Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-8302-1821
Shahin AkhondzadehResearch Center for War-affected People, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-2277-5101

Funding

Tehran University of Medical Sciences 57749
6 · The paper itself

Abstract

Background: Studies on the burden and epidemiological aspects of substance-use disorders in the Middle East and North Africa (MENA) are limited. Aims: To evaluate the burden and epidemiology of substance-use disorders in MENA countries during 1990-2019. Study Design: Ecological study. Methods: Data from the global burden of disease study were used in the current study. The incidence, prevalence, mortality, years of life lost from mortality, years of healthy life lost due to disability, and disability-adjusted life years (DALY) rates attributable to each group of disorders across age groups, genders, years, and countries were retrieved along with their corresponding age-standardized values. Age-standardized DALYs rates of alcohol-use disorders, drug-use disorders, and substanceuse disorders associated with sociodemographic index across MENA countries and over 30 years were examined. Results: The age-standardized DALY rate of substance-use disorders in MENA had risen from 190.1 in 1990 to 234.93 per 100,000 in 2019, indicating a 23.57% increase. In both genders, the DALY rate was highest in the 25-29-years age group in 2019 (440.81 per 100,000 in females and 645.97 per 100,000 in males). In addition, in 2019, age-standardized DALY rates of alcohol-use disorder were the highest in the United Arab Emirates (77.08 per 100,000), Afghanistan (67.77 per 100,000), and Bahrain (60.35 per 100,000). In almost all these countries, opioid-use disorder had the highest age-standardized DALY rate in 2019. Conclusion: The burden of substance-use disorders has increased from 1990 to 2019 in the MENA region in contrast to the global trend. This study findings highlight that the current interventions and laws implemented in this region to address drug trafficking and substance-use disorders may be insufficient and ineffective, warranting further international collaboration and implementation of more effective strategies to reduce the overall burden of substance-use disorders.

Indexed as

Cost of IllnessSubstance-Related DisordersAdolescentAdultAfrica, NorthernAgedDisability-Adjusted Life YearsFemaleGlobal Burden of DiseaseHumansIncidenceMaleMiddle AgedMiddle EastPrevalence

Identifiers

PMID40033654
PMCPMC11881533

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.