Evidence map›Paper›PMID 40033423›Full record

ReviewFluids and barriers of the CNS2025

Research priorities for non-invasive therapies to improve hydrocephalus outcomes.

Alexandra Hochstetler, Christine Hehnly, William Dawes, Daniel Harris, Cameron Sadegh, Francesco T Mangano, Samantha N Lanjewar, Monica J Chau

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Fluids and barriers of the CNS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandra HochstetlerDepartment of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
Christine HehnlyDepartment of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
William DawesDepartment of Paediatric Neurosurgery, Oxford University Hospital, Oxford, UK.
Daniel HarrisAmazon.Com, Inc, Seattle, WA, 98109, USA.
Cameron SadeghDepartment of Neurosurgery, University of California-Davis, Sacramento, CA, 95817, USA.
Francesco T ManganoDivision of Neurosurgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.
Samantha N LanjewarResearch Department, Hydrocephalus Association, Bethesda, MD, 20814, USA.
Monica J ChauResearch Department, Hydrocephalus Association, Bethesda, MD, 20814, USA. research@hydroassoc.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Hydrocephalus Association organized two workshops with the support of the Rudi Schulte Research Institute and Cincinnati Children's Hospital Medical Center entitled "Developing Non-Invasive Hydrocephalus Therapies: Molecular and Cellular Targets", held September 27-29, 2023, in Dallas, TX, and "Developing Non-Invasive Hydrocephalus Therapies: Advancing Towards Clinical Trials", held April 12-13, 2024, in Cincinnati, OH. The goal of these workshops was to explore the frontiers of ongoing research for non-invasive therapies for the treatment of hydrocephalus across all etiologies and to improve patient outcomes at all stages of diagnosis and management. During the consensus-building discussions throughout the research workshops, basic, translational, and clinical scientists aimed to identify the next steps to develop novel treatments for hydrocephalus. This detailed report discusses the research priorities that emerged from these workshops to inspire researchers and guide studies towards better treatment for people living with hydrocephalus.

Indexed as

Biomedical ResearchHydrocephalusHumansAdjuvant therapiesClinical trialsCollaborationHydrocephalusPharmacotherapiesPreclinical models

Identifiers

PMID40033423
PMCPMC11877769

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.