ArticleKnee surgery & related research2025
Do knee alignment patterns differ between Middle Eastern and East Asian populations? A propensity-matched analysis using artificial intelligence.
Article in Knee surgery & related research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Posterior Plate Positioning Without Distal Placement in Medial Closing-Wedge Distal Femoral Osteotomy.Orthopaedic journal of sports medicine · 2026Article
- Artificial intelligence in orthopedics: current applications, challenges, and future directions.Knee surgery & related research · 2026Review
- Dynamic changes to the tibiofemoral joint line with increasing osteoarthritis severity and its relationship to constitutional alignment : a radiological analysis of 3,320 knees.Bone & joint open · 2026Article
- Validation of an Intraoperative Visual Assessment System Based on Bone Mechanical Properties for Selection of Cementless Total Knee Arthroplasty in an Asian Cohort.Journal of clinical medicine · 2026Article
- Coronal plane alignment of the knee phenotypes and ankle joint coronal plane alignment patterns in Egyptian population.World journal of orthopedics · 2026Article
- Combined ACL and ALL Reconstruction Using Allografts as the ACL Graft Source Reduces Surgical Failure and Improves Graft Maturity Compared with Isolated ACL Reconstruction.Journal of clinical medicine · 2026Article
- Novel Visual Grade and Hounsfield Unit Predict Adequate Bone Strength for Cementless Total Knee Arthroplasty.Medicina (Kaunas, Lithuania) · 2025Article
- Central Bone Mineral Density Is Not a Reliable Surrogate for Assessing Suitable Bone Strength for Cementless Total Knee Arthroplasty.Journal of clinical medicine · 2025Article
- Volumetric Bone Mineral Density Assessed by Dual-Energy CT Predicts Bone Strength Suitability for Cementless Total Knee Arthroplasty.Medicina (Kaunas, Lithuania) · 2025Article
- Clinical Efficacy and Safety of Two Cycles of Intra-Articular Injection of Porcine Atelocollagen Versus Hyaluronic Acid in Knee Osteoarthritis.Bioengineering (Basel, Switzerland) · 2025Article
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Authors and funding
6 authors.
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Abstract
introductionPopulation-based differences in knee alignment patterns may impact osteoarthritis (OA) progression. This study compares lower extremity alignment in knee OA between Middle Eastern (UAE) and East Asian (South Korean) populations using artificial intelligence (AI)-assisted analysis.
methodsA retrospective review included patients with knee symptoms from South Korea (2009-2019) and the United Arab Emirates (UAE) (2015-2024). Exclusion criteria comprised prior knee surgeries, significant bony attrition, and low-quality radiographs. Propensity score matching controlled for age and sex differences between populations. Alignment parameters (hip-knee-ankle angle (HKA), medial proximal tibial angle (MPTA), lateral distal femoral angle (LDFA), and joint line convergence angle (JLCA)) and OA severity (Kellgren-Lawrence (KL) grade) were measured using artificial intelligence (AI) software, along with the analysis of coronal plane alignment of the knee (CPAK) classification. Subanalyses by sex and age group (under 40, 40-60, and over 60 years) were also conducted.
resultsA total of 1098 UAE and 7138 South Korean patients (2196 and 14,276 knees, respectively) were evaluated in this study. Post-matching (1:2), body mass index was significantly higher in UAE patients (p < 0.001). CPAK type 1 was predominant in UAE male patients (42.4%), whereas type 2 was more common in South Korean male patients (30.6%). Female patients in both populations predominantly exhibited CPAK type 2 (UAE 30.6%; South Korea 35.3%). UAE patients showed a lower MPTA with increasing age, indicating a trend toward more varus alignment in older individuals.
conclusionsA propensity score-matched analysis revealed significant alignment differences between Middle Eastern and East Asian populations, underscoring the importance of population-specific considerations in OA management.
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