ReviewLipids in health and disease2025
Fatty acid composition in the vaginal tract of cis-gender women: canary in coal mines for reproductive health?
Review in Lipids in health and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Advances in multi-omics and aging clock research for female reproductive health and aging.MedScience · 2026Review
- Volatile organic compound profiling by HS-GC-IMS for vaginal infection identification.Frontiers in cellular and infection microbiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The vaginal tract of cis-gender women of reproductive age is inhabited by communities of bacteria generally dominated by one of four Lactobacillus species. These bacteria are important for the reproductive health of women and favor better outcomes, including fertility, pregnancy leading to term and protection against infections. Past studies have focused on the role of carbohydrates in the balance of vaginal communities, and the role of fatty acids has been underestimated. However, small- to long-chain fatty acids present few properties that, in combination with sugar metabolism, affect the outcomes of the health or disease within the vaginal communities. Herein, we explore the origins of fatty acids in the vaginal tract as well as their roles in the bacterial life cycle in this environment. We also detail the putative impact of vaginal FAs on S. aureus, one of the etiologic agents of aerobic vaginitis. Finally, we discuss their potential for prevention or therapy in women of reproductive age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.