Evidence map›Paper›PMID 40033222›Full record

ArticleBMC cancer2025

Long-term outcomes and survival rates of renal cell carcinoma patients in Erbil, Iraq: a follow-up study.

Fahmi Mohammed Salih, Sami Saleem Omar, Hawro Taha Hamza, Karez Sarbast Namiq, Hana Rizgar Mohammed Ameen, Kakil Ibrahim Rasul, Sherzad Ali Ismael

Abstract read
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fahmi Mohammed SalihMedical Oncologist, Rizgary Oncology Center, Erbil, KRG, Iraq.
Sami Saleem OmarMedical Oncologist, Rizgary Oncology Center, Erbil, KRG, Iraq.
Hawro Taha HamzaMedical Oncologist, Nanakali Hospital for Blood Diseases & Cancer, Erbil, KRG, Iraq.
Karez Sarbast NamiqMedical Oncologist, Nanakali Hospital for Blood Diseases & Cancer, Erbil, KRG, Iraq.
Hana Rizgar Mohammed AmeenMedical Oncologist, Rizgary Oncology Center, Erbil, KRG, Iraq.
Kakil Ibrahim RasulDepartment of Medical Oncology, Hamad Medical Corporation, National Center Cancer Care and Research, Doha, Qatar.
Sherzad Ali IsmaelCommunity Medicine and Public Health, Head of Faculty of Public Health, Kurdistan Board of Medical Specialties, Erbil, KRG, Iraq. sherzad.aismael@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRenal cell carcinoma (RCC) is a heterogeneous group of cancers originating from renal tubular and epithelial cells, constituting 2-4% of global cancer cases. Incidence patterns vary internationally, with the Czech Republic and European Baltic countries experiencing higher rates. Despite the majority of cases being sporadic, approximately 4% have a hereditary basis.

methodsThis study, conducted in Erbil, Iraq, investigates RCC survival rates and influential factors at Nanakaly Hospital and Rizgary Oncology Center. A retrospective analysis spanning January 2017 to December 2020, covering 93 patients, explores demographic, clinical, and treatment variables.

resultsOut of a total of 93 cases, there were 68 deaths, and 25 cases were censored. This means that 73.12% of the cases resulted in death, and 26.88% of the cases were censored. The Kaplan-Meier survival analysis indicates a mean survival time of approximately 5.517 years. Clinical characteristics such as tumor side and histology show no significant associations with survival status, except for the TNM stage (p-value < 0.001). While smoking, alcohol history, history of malignancy, and comorbidities demonstrate no significant impact on survival, the study identifies a potential trend associating comorbidities with poorer outcomes (p-value = 0.051). Significant associations emerge with treatment types; radical nephrectomy (p-value = 0.004) and systemic treatments (p-value < 0.001) influence survival. Strikingly, recurrence was significantly associated with mortality (p-value < 0.001).

conclusionsThe study reveals a higher RCC had a shorter survival in Erbil compared to international survival. This is attributed to delayed referrals and advanced disease stages. Additionally, the absence of crucial antineoplastic agents negatively affects outcomes. Comorbidities are also found to significantly reduce survival rates. These findings underscore the necessity for an enhanced referral system, improved access to oncological services, and the approval of essential therapies in Erbil.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsAdultAgedAged, 80 and overFemaleFollow-Up StudiesHumansIraqKaplan-Meier EstimateMaleMiddle AgedNeoplasm StagingNephrectomyPrognosisRetrospective StudiesErbil IraqNanakali hospitalRenal cell carcinomaRzgary oncology centerSurvival analysis

Identifiers

PMID40033222
PMCPMC11874839

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.