Evidence map›Paper›PMID 40033213›Full record

SynthesisBMC neuroscience2025

A systematic review of the therapeutic potential of nicotinamide adenine dinucleotide precursors for cognitive diseases in preclinical rodent models.

Musaab Abdulrazzaq Qader, Leila Hosseini, Nasrin Abolhasanpour, Farnaz Oghbaei, Leila Maghsoumi-Norouzabad, Hanieh Salehi-Pourmehr, Fatemeh Fattahi, Reza Naghdi Sadeh

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. NADAlzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Musaab Abdulrazzaq QaderResearch Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Leila HosseiniResearch Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Iran. leilahosseini337@gmail.com.ORCID 0000-0002-4203-4618
Nasrin AbolhasanpourResearch Center for Evidence-Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Farnaz OghbaeiDepartment of Basic Medical Sciences, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Leila Maghsoumi-NorouzabadTraditional Medicine and Hydrotherapy Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.
Hanieh Salehi-PourmehrResearch Center for Evidence-Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Fatemeh FattahiDepartment of Medical Genetics, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Reza Naghdi SadehResearch Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Iran. naghdir@tbzmed.ac.ir.ORCID 0000-0002-3541-812X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review sought to assess the impact of nicotinamide adenine dinucleotide (NAD

Indexed as

Cognitive DysfunctionNADAnimalsDisease Models, AnimalHumansMitochondriaOxidative StressRatsNADCognitive impairmentInflammationMemoryMitochondrial dysfunctionNicotinamideOxidative stress

Identifiers

PMID40033213
PMCPMC11877801

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.