Evidence map›Paper›PMID 40033140›Full record

ArticleNature microbiology2025

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer.

Bhupesh Kumar Thakur, Yann Malaise, Saurav Roy Choudhury, Anna Neustaeter, Williams Turpin, Catherine Streutker, Julia Copeland, Erin O Y Wong, William W Navarre, David S Guttman and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Harnessing the microbiome for cancer therapy.Nature reviews. Microbiology · 2026
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. A triple threat in colorectal cancer.Nature reviews. Microbiology · 2025
    Article
  16. Article
  17. Hepatoprotective Potential ofIn vivo (Athens, Greece)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Bhupesh Kumar ThakurDepartment of Immunology, University of Toronto, Toronto, Ontario, Canada.
Yann MalaiseDepartment of Immunology, University of Toronto, Toronto, Ontario, Canada.
Saurav Roy ChoudhuryDepartment of Immunology, University of Toronto, Toronto, Ontario, Canada.
Anna NeustaeterDivision of Gastroenterology, Department of Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada.
Williams TurpinDivision of Gastroenterology, Department of Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada.
Catherine StreutkerDepartment of Laboratory Medicine, Unity Health Toronto, Toronto, Ontario, Canada.
Julia CopelandCentre for the Analysis of Genome Evolution & Function, University of Toronto, Toronto, Ontario, Canada.
Erin O Y WongDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
William W NavarreDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-9293-9220
David S GuttmanCentre for the Analysis of Genome Evolution & Function, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-8479-3869
Christian JobinDepartment of Infectious Diseases and Pathology, University of Florida College of Veterinary Medicine, Gainesville, FL, USA.ORCID http://orcid.org/0000-0002-3733-1001
Kenneth CroitoruDivision of Gastroenterology, Department of Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0003-1231-0180
Alberto MartinDepartment of Immunology, University of Toronto, Toronto, Ontario, Canada. alberto.martin@utoronto.ca.ORCID http://orcid.org/0000-0002-1260-7710

Funding

Gouvernement du Canada | Instituts de Recherche en Santé du Canada | CIHR Skin Research Training Centre (Skin Research Training Centre) PJT-173501
6 · The paper itself

Abstract

Diet, microbiome, inflammation and host genetics have been linked to colorectal cancer development; however, it is not clear whether and how these factors interact to promote carcinogenesis. Here we used Il10

Indexed as

Colorectal NeoplasmsDietary FiberEscherichia coliPeptidesPolyketidesAnimalsCarcinogenesisDisease Models, AnimalDNA DamageGastrointestinal MicrobiomeInflammationInterleukin-10MaleMiceMice, Inbred C57BLMice, KnockoutcolibactinDietary FiberInterleukin-10PeptidesPolyketidesPPAR gamma

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.