ArticleEuropean journal of clinical nutrition2025
High prevalence of low vitamin D status in the Czech Republic: a retrospective study of 119,925 participants.
Article in European journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Vitamin D and Health: Establishing Causal Relationships Through Observational Evidence and Hill's Criteria in a Biological Framework.Nutrients · 2026Review
- Obesity and Health Risk Factors in Czech Artillery Soldiers.Military medicine · 2026Article
- Determinants of Vitamin D Status: An Analysis in a Primary Care Setting in Lithuania of Age, Gender and Seasonality.Medicina (Kaunas, Lithuania) · 2026Article
- Molecular insights into the role of vitamin D in atopic dermatitis: pathogenesis, diagnosis, and emerging therapies.Frontiers in immunology · 2026Review
- Vitamin D Supplementation in the Czech Republic: Socioeconomic Determinants and Public Awareness Gaps.Nutrients · 2025Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesGiven the high worldwide prevalence of vitamin D deficiency and its role in numerous diseases affecting mortality and morbidity, this study seeks to determine the prevalence of low 25-hydroxyvitamin D levels in the Czech Republic, where population-level data are currently lacking. STUDY
designThis retrospective study utilized a large dataset to analyze 25-hydroxyvitamin D levels over an extended period.
methodsWe analyzed data from 119,925 individuals aged 0-100 years categorizing them as sufficient (75-250 nmol/L), insufficient (50-75 nmol/L), or deficient (<50 nmol/L). We also examined levels of CRP, homocysteine, and their correlations with 25-hydroxyvitamin D levels across age groups. Age, sex, sampling month, sunlight exposure (monthly and annual), and influenza virus positivity were assessed for their relationship with the 25-hydroxyvitamin D levels.
resultsThe study found a high prevalence of 25-hydroxyvitamin D inadequacy, with sufficient levels observed in 65.6% of infants (0-12 months). The lowest prevalence of sufficiency was in the 6-15 years (19.2%) and 16-30 years (22.1%) groups. The highest deficiency prevalence was in the 91-100 years group (51.8%). 25-hydroxyvitamin D levels in all age groups and both sexes correlated with all selected parameters. Lower sun exposure, higher flu virus positivity, male gender, and elevated homocysteine and CRP levels were negatively correlated with 25-hydroxyvitamin D levels.
conclusionsThe prevalence of 25-hydroxyvitamin D inadequacy in the Czech Republic is high. It is advisable to consider testing, monitoring, and providing medical recommendations for vitamin D supplementation as part of health prevention strategies in the general population.
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