Trial reportNature medicine2025
Task-sharing and telemedicine delivery of psychotherapy to treat perinatal depression: a pragmatic, noninferiority randomized trial.
Trial report in Nature medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04153864 (Scaling Up Maternal Mental Healthcare by Increasing Access to Treatment), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Scaling Up Maternal Mental Healthcare by Increasing Access to Treatment (SUMMIT): A Pragmatic, Non-inferiority Trial for Perinatal Depression and Anxiety
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Which therapy works best for maternal depressive symptoms? A network meta-analysis of psychotherapeutic interventions.Archives of women's mental health · 2026Pooled it
- Different psychological interventions for perinatal depression: a systematic review and meta-analysis of randomized controlled trials.BMC psychiatry · 2025Pooled it
- Cognitive Behavioral Immersion for Depression: Randomized Controlled Trial Comparing Virtual Reality and Flat-Screen Delivery.Journal of medical Internet research · 2026Trial
- Bridges to treatment satisfaction: the roles of trauma, social support, race and ethnicity among perinatal women receiving behavioural activation therapy.BMC medicine · 2025Trial
- Evaluating the costs of developing a digital supervision tool for task-shared depression care: findings from a multi-site study in India.BJPsych open · 2026Article
- Plasma Metabolomic and Proteomic Profiling of the Mechanisms Underlying the Cumulative Impact of Co-occurring Psychiatric Disorders on Atopic Dermatitis.Acta dermato-venereologica · 2026Article
- Bridging Gaps in Perinatal Mental Health: A Review of Peer and Non-specialist Supports for Racially, Ethnically and Culturally Diverse Communities in the U.S.Current psychiatry reports · 2026Review
- Advances in Perinatal Depression: A Focus on Screening and Treatment.Journal of clinical medicine · 2026Review
- Effectiveness of psychological interventions for reducing depressive symptoms among women experiencing perinatal depression: a systematic review.AJOG global reports · 2026Review
- Innovations to improve outcomes and uptake of psychotherapies for mental disorders: a state-of-the-art review.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- The Reproductive Mental health of Ontario Virtual Intervention Network (MOVIN): a pilot randomized controlled trial.Communications medicine · 2026Article
- The intergenerational legacies of research disinvestment, aid retrenchment and transactional compacts on global women's health.PLOS global public health · 2026Article
- Comparing standard and technology-assisted peer-delivered CBT for perinatal depression: A causal mediation study.Global mental health (Cambridge, England) · 2026Article
- Scaling Up Task-Shared Depression Care in Texas: Evaluating the Preliminary Effectiveness and Acceptability of a Digital Program for Training Non-Specialist Providers.Psychiatric research and clinical practice · 2026Article
- Exploring the influence of personality and partner attachment on perinatal depression and anxiety.BMC psychology · 2025Article
- Development and initial evaluation of an ultra-brief digital treatment for perinatal depression and anxiety symptoms.Internet interventions · 2025Article
- Behavioral Activation for Perinatal Suicide Ideation: Secondary Analysis of a Noninferiority Randomized Clinical Trial.JAMA psychiatry · 2025Article
- Advancing telemedicine and task-sharing to improve access to psychotherapy for perinatal populations.Communications medicine · 2025Article
- Building the Infrastructure for Sustainable Digital Mental Health: It Is "Prime Time" for Implementation Science.JMIR mental health · 2025Article
- An exploratory study of the relevance of therapy format and therapist' training in individual cognitive behavioral therapy for psychosis.Frontiers in psychiatry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors.
Funding
Abstract
Task-sharing and telemedicine can increase access to effective psychotherapies. Scaling Up Maternal Mental healthcare by Increasing access to Treatment (SUMMIT) is pragmatic, multisite, noninferiority, four-arm trial that tested the non-inferiority of provider (non-specialist vs. specialist providers) and modality (telemedicine vs. in-person) in delivering psychotherapy for perinatal depressive symptoms. Across three university-affiliated networks in the United States and Canada, pregnant and postpartum adult participants were randomized 1:1:1:1 to each arm (472 nonspecialist telemedicine, 145 nonspecialist in-person, 469 specialist telemedicine and 144 specialist in-person) and offered weekly behavioral activation treatment sessions. The primary outcome was depressive symptoms (Edinburgh Postnatal Depression Scale (EPDS)) and the secondary outcome was anxiety (Generalized Anxiety Disorder (GAD-7)) symptoms at 3 months post-randomization. Between 8 January 2020 and 4 October 2023, 1,230 participants were recruited. Noninferiority was met for the primary outcome comparing provider (EPDS: nonspecialist 9.27 (95% CI 8.85-9.70) versus specialist 8.91 (95% CI 8.49-9.33)) and modality (EPDS: telemedicine 9.15 (95% CI 8.79-9.50) versus in-person 8.92 (95% CI 8.39-9.45)) for both intention-to-treat and per protocol analyses. Noninferiority was also met for anxiety symptoms in both comparisons. There were no serious or adverse events related to the trial. This trial suggests compelling evidence for task-sharing and telemedicine to improve access to psychotherapies for perinatal depressive and anxiety symptoms. ClinicalTrials.gov NCT04153864.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.