Evidence map›Paper›PMID 40032940›Full record

ArticleScientific reports2025

An enzyme/pH dual-responsive supramolecular fluorescent vesicle with tunable size fabricated by europium complex and polypseudorotaxanes.

S J Yi, F Li, Y Y Jiao, X X Liu, J J Li, W M Gao, X D Guo, J Wang

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

S J Yi *Department of Basic Science, Shanxi Agricultural University, Taigu, 030801, China. yisijing@139.com.
F Li *Department of Basic Science, Shanxi Agricultural University, Taigu, 030801, China.
Y Y JiaoDepartment of Chemistry, China Agricultural University, Beijing, 100193, China.
X X LiuDepartment of Basic Science, Shanxi Agricultural University, Taigu, 030801, China.
J J LiDepartment of Basic Science, Shanxi Agricultural University, Taigu, 030801, China.
W M GaoDepartment of Basic Science, Shanxi Agricultural University, Taigu, 030801, China.
X D GuoDepartment of Basic Science, Shanxi Agricultural University, Taigu, 030801, China.
J WangDepartment of Chemistry, Taiyuan Normal University, Jinzhong, 030619, China.

Funding

National Natural Science Foundation of China 22002077Science and Technology Innovation Foundation of Shanxi Agricultural University No. 2017YJ36 and 2017YJ42Shanxi Province Basic Research Program Youth Science and Technology Research Fund No. 202103021223332
6 · The paper itself

Abstract

The fluorescent vesicles based on lanthanide ions are considered as an ideal biomimetic optical nanoplatform for simulating biological processes of cell membrane. However, the accurately and controllably adjusting the size of vesicles based on lanthanides while ensuring their fluorescence performance and stability still remains a challenge. Herein, a dual-stimuli-responsive fluorescent supramolecular vesicle with tunable size has been designed based on host-guest interaction and coordinating aggregation. Europium complexes can be encapsulated within supramolecular assemblies by assembling with polypseudorotaxanes (PPRs), which are formed by F127 and carboxymethyl-β-cyclodextrin (CMCD) through host-guest interaction. The fluorescence properties of the europium complexes have been significantly enhanced by confining and shielding them within vesicles. Upon the addition of α-amylase and HCl, the fluorescence intensity of the vesicles will gradually and significantly quench as a result of CMCD degradation and dissociation of the europium complexes. This research presents a convenient method for regulating the size of lanthanide fluorescent vesicles, and the supramolecular vesicles obtained with multi-stimuli response are anticipated to be utilized in the diagnosis of relevant diseases and targeted drug delivery.

Indexed as

Coordination ComplexesEuropiumFluorescent DyesRotaxanesFluorescenceHydrogen-Ion ConcentrationParticle SizeCoordination ComplexesEuropiumFluorescent DyesRotaxanesCyclodextrinEuropium complexFluorescence quenchingHost-guest interactionStimuli-responsive

Identifiers

PMID40032940
PMCPMC11876579

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.