Evidence map›Paper›PMID 40032878›Full record

ReviewNature communications2025

A long road ahead to reliable and complete medicinal plant genomes.

Ling-Tong Cheng, Zi-Long Wang, Qian-Hao Zhu, Min Ye, Chu-Yu Ye

Abstract readReview
In one paragraph

Review in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  12. Chromosome-Level Genome Assembly ofPlants (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ling-Tong ChengInstitute of Crop Science, Zhejiang Key Laboratory of Crop Germplasm Innovation and Utilization, Zhejiang University, Hangzhou, China.
Zi-Long WangState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.ORCID http://orcid.org/0000-0002-7875-0704
Qian-Hao ZhuCSIRO Agriculture and Food, Canberra, Australia.ORCID http://orcid.org/0000-0002-6505-7417
Min YeState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.ORCID http://orcid.org/0000-0002-9952-2380
Chu-Yu YeInstitute of Crop Science, Zhejiang Key Laboratory of Crop Germplasm Innovation and Utilization, Zhejiang University, Hangzhou, China. yecy@zju.edu.cn.ORCID http://orcid.org/0000-0003-0903-0356

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-read DNA sequencing has propelled medicinal plant genomics forward, with over 400 genomes from 203 plants sequenced by February 2025. However, many genomes still have assembly and annotation flaws, with only 11 gapless telomere-to-telomere assemblies. The core challenge remains identifying genes linked to secondary metabolite biosynthesis, regulation and evolution. High-quality complete genomes are essential for characterizing biosynthetic gene clusters and for enabling robust functional genomics and synthetic biology applications. We propose to focus on achieving more complete genome assemblies in diverse varieties on the basis of refining the currently available ones, leverage lessons from crop genomics research, and apply the cutting-edge genomics technologies in research of medicinal plant genomics.

Indexed as

Genome, PlantGenomicsPlants, MedicinalMolecular Sequence AnnotationSequence Analysis, DNA

Identifiers

PMID40032878
PMCPMC11876585

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.