Evidence map›Paper›PMID 40032813›Full record

ArticleRadiological physics and technology2025

Comparative analysis of radiotherapy modalities and techniques for left breast cancer: dose coverage, setup accuracy, with patient-specific selection criteria for applying deep inspiration breath hold.

Masud Parvej, Cristina Cappelletto, Angela Caroli, Lorenzo Vinante, Annalisa Drigo, Paola Chiovati

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Radiological physics and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masud ParvejDepartment of Physics, Oakland University, Rochester, MI, USA. parvej.baec@gmail.com.ORCID http://orcid.org/0009-0006-5053-5881
Cristina CappellettoMedical Physics Department, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Via F. Gallini 2, 33081, Aviano, Italy.
Angela CaroliRadiation Oncology Department, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Via F. Gallini 2, 33081, Aviano, Italy.
Lorenzo VinanteRadiation Oncology Department, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Via F. Gallini 2, 33081, Aviano, Italy.
Annalisa DrigoMedical Physics Department, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Via F. Gallini 2, 33081, Aviano, Italy.
Paola ChiovatiMedical Physics Department, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Via F. Gallini 2, 33081, Aviano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To compare dosimetric outcomes between Free Breath (FB) and Deep Inspiration Breath Hold (DIBH) across different radiotherapy modalities, establish patient selection criteria for DIBH, and optimizing the setup margin (SM) in left breast cancer treatment. 26 patients with left breast cancer were studied at CRO, Aviano in Italy. FB and DIBH simulations were done using CT with a real-time position management system. 3DCRT and IMRT plans were prepared for both simulations of each patient. The setup margin was measured by Van Herk's formula and compared with residual uncertainties. The dose coverage of PTV and spare OARs were better with DIBH. The distance of more than 1.6 cm between (Left Anterior Descending artery) LAD and PTV was no significantly different for FB and DIBH. The setup margin by Van Herk's formula was calculated as 0.9 cm for DIBH_IMRT. The average duration of DIBH per respiration was 19 ± 4 s. So, holding one breath at least 19 s would be the criteria for choosing a patient to apply DIBH. DIBH enhances PTV dose coverage and OAR sparing in both 3DCRT and IMRT. When the distance between the LAD and PTV exceeds 1.6 cm, the application of DIBH depends on the availability of a LINAC with RPM and the patient's breathholding ability.

Indexed as

Breast NeoplasmsBreath HoldingPatient SelectionRadiation DosageUnilateral Breast NeoplasmsAgedFemaleHumansMiddle AgedOrgans at RiskRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-Assisted

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.